| Description : |
This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
149.6 kDa |
| AA Sequence : |
MGDPAPARSLDDIDLSALRDPAGIF ELVEVVGNGTYGQVYKGRHVKTGQL AAIKVMDVTEDEEEEIKQEINMLKK YSHHRNIATYYGAFIKKSPPGNDDQ LWLVMEFCGAGSVTDLVKNTKGNAL KEDCIAYICREILRGLAHLHAHKVI HRDIKGQNVLLTENAEVKLVDFGVS AQLDRTVGRRNTFIGTPYWMAPEVI ACDENPDATYDYRSDIWSLGITAIE MAEGAPPLCDMHPMRALFLIPRNPP PRLKSKKWSKKFIDFIDTCLIKTYL SRPPTEQLLKFPFIRDQPTERQVRI QLKDHIDRSRKKRGEKEETEYEYSG SEEEDDSHGEEGEPSSIMNVPGEST LRREFLRLQQENKSNSEALKQQQQL QQQQQRDPEAHIKHLLHQRQRRIEE QKEERRRVEEQQRREREQRKLQEKE QQRRLEDMQALRREEERRQAEREQE YKRKQLEEQRQSERLQRQLQQEHAY LKSLQQQQQQQQLQKQQQQQLLPGD RKPLYHYGRGMNPADKPAWAREVEE RTRMNKQQNSPLAKSKPGSTGPEPP IPQASPGPPGPLSQTPPMQRPVEPQ EGPHKSLVAHRVPLKPYAAPVPRSQ SLQDQPTRNLAAFPASHDPDPAIPA PTATPSARGAVIRQNSDPTSEGPGP SPNPPAWVRPDNEAPPKVPQRTSSI ATALNTSGAGGSRPAQAVRARPRSN SAWQIYLQRRAERGTPKPPGPPAQP PGPPNASSNPDLRRSDPGWERSDSV LPASHGHLPQAGSLERNRVGASSKL DSSPVLSPGNKAKPDDHRSRPGRPA DFVLLKERTLDEAPRPPKKAMDYSS SSEEVESSEDDEEEGEGGPAEGSRD TPGGRSDGDTDSVSTMVVHDVEEIT GTQPPYGGGTMVVQRTPEEERNLLH ADSNGYTNLPDVVQPSHSPTENSKG QSPPSKDGSGDYQSRGLVKAPGKSS FTMFVDLGIYQPGGSGDSIPITALV GGEGTRLDQLQYDVRKGSVVNVNPT NTRAHSETPEIRKYKKRFNSEILCA ALWGVNLLVGTENGLMLLDRSGQGK VYGLIGRRRFQQMDVLEGLNLLITI SGKRNKLRVYYLSWLRNKILHNDPE VEKKQGWTTVGDMEGCGHYRVVKYE RIKFLVIALKSSVEVYAWAPKPYHK FMAFKSFADLPHRPLLVDLTVEEGQ RLKVIYGSSAGFHAVDVDSGNSYDI YIPVHIQSQITPHAIIFLPNTDGME MLLCYEDEGVYVNTYGRIIKDVVLQ WGEMPTSVAYICSNQIMGWGEKAIE IRSVETGHLDGVFMHKRAQRLKFLC ERNDKVFFASVRSGGSSQVYFMTLN RNCIMNWTRTRPLEQKLISEEDLAA NDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
