Recombinant Human MKNK2 Protein (T72-R385), Tag Free
Cat.No. : | MKNK2-1164H |
Product Overview : | Recombinant Human MKNK2(T72-R385) Protein was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Serine/threonine-protein kinase that phosphorylates SFPQ/PSF, HNRNPA1 and EIF4E. May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. Required for mediating PP2A-inhibition-induced EIF4E phosphorylation. Triggers EIF4E shuttling from cytoplasm to nucleus. Isoform 1 displays a high basal kinase activity, but isoform 2 exhibits a very low kinase activity. Acts as a mediator of the suppressive effects of IFNgamma on hematopoiesis. Negative regulator for signals that control generation of arsenic trioxide As(2)O(3)-dependent apoptosis and anti-leukemic responses. Involved in anti-apoptotic signaling in response to serum withdrawal. |
Source : | E. coli |
Species : | Human |
Tag : | No tag |
Form : | Liquid |
Protein Length : | T72-R385 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | MKNK2 MAP kinase interacting serine/threonine kinase 2 [ Homo sapiens (human) ] |
Official Symbol : | MKNK2 |
Synonyms : | MKNK2; MAP kinase interacting serine/threonine kinase 2; G protein coupled receptor kinase 7, GPRK7; MAP kinase-interacting serine/threonine-protein kinase 2; MNK2; Putative map kinase interacting kinase; MAPK signal-integrating kinase 2; G protein-coupled receptor kinase 7; MAP kinase signal-integrating kinase 2; GPRK7; |
Gene ID : | 2872 |
mRNA Refseq : | NM_017572 |
Protein Refseq : | NP_060042 |
MIM : | 605069 |
UniProt ID : | Q9HBH9 |
Products Types
◆ Recombinant Protein | ||
MKNK2-3353R | Recombinant Rat MKNK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
MKNK2-5369H | Recombinant Human MKNK2 Protein, GST-tagged | +Inquiry |
MKNK2-1416H | Recombinant Human MKNK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
MKNK2-5574M | Recombinant Mouse MKNK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
MKNK2-38H | Recombinant Human MKNK2 Protein (D228G, 72-385), His tagged | +Inquiry |
◆ Lysates | ||
MKNK2-4302HCL | Recombinant Human MKNK2 293 Cell Lysate | +Inquiry |
MKNK2-4301HCL | Recombinant Human MKNK2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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