| Description : |
The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Fc |
| Form : |
Lyophilized |
| Molecular Mass : |
107.3 kDa |
| Protein Length : |
750 |
| AA Sequence : |
MGKSESQMDITDINTPKPKKKQRWT PLEISLSVLVLLLTIIAVTMIALYA TYDDGICKSSDCIKSAARLIQNMDA TTEPCTDFFKYACGGWLKRNVIPET SSRYGNFDILRDELEVVLKDVLQEP KTEDIVAVQKAKALYRSCINESAID SRGGEPLLKLLPDIYGWPVATENWE QKYGASWTAEKAIAQLNSKYGKKVL INLFVGTDDKNSVNHVIHIDQPRLG LPSRDYYECTGIYKEACTAYVDFMI SVARLIRQEERLPIDENQLALEMNK VMELEKEIANATAKPEDRNDPMLLY NKMTLAQIQNNFSLEINGKPFSWLN FTNEIMSTVNISITNEEDVVVYAPE YLTKLKPILTKYSARDLQNLMSWRF IMDLVSSLSRTYKESRNAFRKALYG TTSETATWRRCANYVNGNMENAVGR LYVEAAFAGESKHVVEDLIAQIREV FIQTLDDLTWMDAETKKRAEEKALA IKERIGYPDDIVSNDNKLNNEYLEL NYKEDEYFENIIQNLKFSQSKQLKK LREKVDKDEWISGAAVVNAFYSSGR NQIVFPAGILQPPFFSAQQSNSLNY GGIGMVIGHEITHGFDDNGRNFNKD GDLVDWWTQQSASNFKEQSQCMVYQ YGNFSWDLAGGQHLNGINTLGENIA DNGGLGQAYRAYQNYIKKNGEEKLL PGLDLNHKQLFFLNFAQVWCGTYRP EYAVNSIKTDVHSPGNFRIIGTLQN SAEFSEAFHCRKNSYMNPEKKCRVW |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
