Recombinant Human MMP13 Protein (E103-N274), His tagged
| Cat.No. : | MMP13-0833H |
| Product Overview : | Recombinant Human 6His-TEV-MMP2(E103-N274) Protein was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
| Description : | Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CCN2. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion. |
| Source : | E. coli |
| Species : | Human |
| Tag : | His |
| Form : | Liquid |
| Protein Length : | E103-N274 |
| Endotoxin : | < 0.01 EU per μg of the protein |
| Purity : | 90% |
| Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
| Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Storage Buffer : | Supplied as sterile 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol |
| Shipping : | It is shipped out with blue ice. |
| Gene Name : | MMP13 matrix metallopeptidase 13 (collagenase 3) [ Homo sapiens (human) ] |
| Official Symbol : | MMP13 |
| Synonyms : | MMP13; matrix metallopeptidase 13 (collagenase 3); matrix metalloproteinase 13 (collagenase 3); collagenase 3; CLG3; MMP-13; MANDP1; |
| Gene ID : | 4322 |
| mRNA Refseq : | NM_002427 |
| Protein Refseq : | NP_002418 |
| MIM : | 600108 |
| UniProt ID : | P45452 |
Products Types
| ◆ Recombinant Protein | ||
| MMP13-2045D | Recombinant Dog MMP13 Protein (28-478 aa), His-SUMO-tagged | +Inquiry |
| MMP13-1119C | Recombinant Cattle MMP13 Protein, His-tagged | +Inquiry |
| MMP13-5598M | Recombinant Mouse MMP13 Protein, His (Fc)-Avi-tagged | +Inquiry |
| MMP13-239H | Recombinant Active Human MMP13 Protein, His-tagged(C-ter) | +Inquiry |
| MMP13-2448H | Recombinant Human MMP13 Protein, His-tagged | +Inquiry |
| ◆ Lysates | ||
| MMP13-4280HCL | Recombinant Human MMP13 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket
