Recombinant Human MMP14 Protein, GST-tagged
Cat.No. : | MMP14-5423H |
Product Overview : | Human MMP14 full-length ORF ( AAH64803.1, 1 a.a. - 582 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 92.3 kDa |
AA Sequence : | MSPAPRPSRCLLLPLLTLGTALASL GSAQSSSFSPEAWLQQYGYLPPGDL RTHTQRSPQSLSAAIAAMQKFYGLQ VTGKADADTMKAMRRPRCGVPDKFG AEIKANVRRKRYAIQGLKWQHNEIT FCIQNYTPKVGEYATYEAIRKAFRV WESATPLRFREVPYAYIREGHEKQA DIMIFFAEGFHGDSTPFDGEGGFLA HAYFPGPNIGGDTHFDSAEPWTVRN EDLNGNDIFLVAVHELGHALGLEHS SDPSAIMAPFYQWMDTENFVLPDDD RRGIQQLYGGESGFPTKMPPQPRTT SRPSVPDKPKNPTYGPNICDGNFDT VAMLRGEMFVFKERWFWRVRNNQVM DGYPMPIGQFWRGLPASINTAYERK DGKFVFFKGDKHWVFDEASLEPGYP KHIKELGRGLPTDKIDAALFWMPNG KTYFFRGNKYYRFNEELRAVDSEYP KNIKVWEGIPESPRGSFMGSDEVFT YFYKGNKYWKFNNQKLKVEPGYPKS ALRDWMGCPSGGRPDEGTEEETEVI IIEVDEEGGGAVSAAAVVLPVLLLL LVLAVGLAVFFFRRHGTPRRLLYCQ RSLLDKV |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | MMP14 matrix metallopeptidase 14 (membrane-inserted) [ Homo sapiens ] |
Official Symbol : | MMP14 |
Synonyms : | MMP14; matrix metallopeptidase 14 (membrane-inserted); matrix metalloproteinase 14 (membrane inserted); matrix metalloproteinase-14; membrane type 1 metalloprotease; MT1 MMP; membrane-type matrix metalloproteinase 1; membrane-type-1 matrix metalloproteinase; matrix metalloproteinase 14 (membrane-inserted); 1; MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; MT1-MMP; MT-MMP 1; |
Gene ID : | 4323 |
mRNA Refseq : | NM_004995 |
Protein Refseq : | NP_004986 |
MIM : | 600754 |
UniProt ID : | P50281 |
Products Types
◆ Recombinant Protein | ||
MMP14-2611R | Recombinant Rhesus Macaque MMP14 Protein, His (Fc)-Avi-tagged | +Inquiry |
Mmp14-4098M | Recombinant Mouse Mmp14 Protein, Myc/DDK-tagged | +Inquiry |
MMP14-3369R | Recombinant Rat MMP14 Protein, His (Fc)-Avi-tagged | +Inquiry |
MMP14-571H | Recombinant Human MMP14 Protein, MYC/DDK-tagged | +Inquiry |
MMP14-1418H | Recombinant Human MMP14 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
MMP14-4279HCL | Recombinant Human MMP14 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2123 | MMP-14 Inhibitor Screening Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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