Recombinant Human MPO, GST-tagged
| Cat.No. : | MPO-29360TH |
| Product Overview : | Recombinant fragment with GST tag corresponding to amino acids 621-745 of Human Myeloperoxidase; 125 amino acids, 40kDa. |
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| Description : | Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain.The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. |
| Conjugation : | GST |
| Source : | E. coli |
| Form : | Liquid |
| Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5 |
| Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
| Sequence Similarities : | Belongs to the peroxidase family. XPO subfamily. |
| Gene Name : | MPO myeloperoxidase [ Homo sapiens ] |
| Official Symbol : | MPO |
| Synonyms : | MPO; myeloperoxidase; |
| Gene ID : | 4353 |
| mRNA Refseq : | NM_000250 |
| Protein Refseq : | NP_000241 |
| MIM : | 606989 |
| Uniprot ID : | P05164 |
| Chromosome Location : | 17q21.3-q23 |
| Pathway : | C-MYB transcription factor network, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; IL23-mediated signaling events, organism-specific biosystem; Phagosome, organism-specific biosystem; Phagosome, conserved biosystem; |
| Function : | chromatin binding; heme binding; heparin binding; metal ion binding; oxidoreductase activity; |
Products Types
| ◆ Recombinant Protein | ||
| MPO-51H | Recombinant Human MPO Protein, His-tagged | +Inquiry |
| Mpo-52M | Recombinant Mouse Mpo Protein, His-tagged | +Inquiry |
| MPO-2943H | Recombinant Human MPO Protein, GST-tagged | +Inquiry |
| MPO-5506H | Recombinant Human MPO Protein, GST-tagged | +Inquiry |
| MPO-527H | Recombinant Human MPO Protein (Met1-Ser745), His-tagged | +Inquiry |
| ◆ Native Protein | ||
| MPO-01H | Active Native Human MPO Protein | +Inquiry |
| MPO-8220H | Native Human Neutrophil Myeloperoxidase | +Inquiry |
| MPO -27H | Active Native Human Myeloperoxidase | +Inquiry |
| ◆ Lysates | ||
| MPO-4234HCL | Recombinant Human MPO 293 Cell Lysate | +Inquiry |
| ◆ Assay kits | ||
| Kit-1986 | Neutrophil Myeloperoxidase Activity Assay Kit | +Inquiry |
| Kit-1982 | Myeloperoxidase Inhibitor Screening Assay Kit | +Inquiry |
| Kit-0604 | MPO Inhibitor Screening Assay Kit | +Inquiry |
| Kit-0607 | Myeloperoxidase Peroxidation Fluorometric Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMPO is synthesized and stored by granulocytes in the bone marrow.
MPO mediates the production of halogenated oxidants in phagosomes and plays a key role in bacterial killing and protecting the body from disease.
Under physiological conditions in the body, MPO catalyzes the production of hypochlorous acid.
MPO can be used as a marker for cerebral stroke.
MPO has been associated with studies of diseases such as leukemia and coronary heart disease.
Customer Reviews (3)
Write a reviewThe technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.
The MPO proteins purchased from your company is suitable for WB.
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