Recombinant Human MPO protein, His-tagged

• Cat.No.: MPO-49H
• Product Overview: Recombinant Human MPO fused with His tag at N-terminal was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: lyophilized from a 0.2um filtered solution in PBS, pH 7.4 with 5% trehalose and 0.01% thimerosal
• Molecular Mass: 65.8kD
• AA Sequence: MKKGHHHHHHLVPRGSCPEQDKYRT ITGMCNNRRSPTLGASNRAFVRWLP AEYEDGFSLPYGWTPGVKRNGFPVA LARAVSNEIVRFPTDQLTPDQERSL MFMQWGQLLDHDLDFTPEPAARASF VTGVNCETSCVQQPPCFPLKIPPN DPRIKNQADCIPFFRSCPACPGSNI TIRNQINALTSFVDASMVYGSEEPL ARNLRNMSNQLGLLAVNQRFQDNG RALLPFDNLHDDPCLLTNRSARIPC FLAGDTRSSEMPELTSMHTLLLREH NRLATELKSLNPRWDGERLYQEAR KIVGAMVQIITYRDYLPLVLGPTAM RKYLPTYRSYNDSVDPRIANVFTNA FRYGHTLIQPFMFRLDNRYQPMEP NPRVPLSRVFFASWRVVLEGGIDPI LRGLMATPAKLNRQNQIAVDEIRER LFEQVMRIGLDLPALNMQRSRDHG LPGYNAWRRFCGLPQPETVGQLGTV LRNLKLARKLMEQYGTPNNIDIWMG GVSEPLKRKGRVGPLLACIIGTQF RKLRDGDRFWWENEGVFSMQQRQAL AQISLPRIICDNTGITTVSKNNIFM SNSYPRDFVNCSTLPALNLASWRE AS
• Purity: Greater than 95% by SDS-PAGE gel analyses.
• Applications: Immunogen for antibody production, immunological and mass myoglobin standard, myoglobin biochemical and immunochemical studies.
• Storage: - 20°C for Lyophilized, - 80°C for Liquid

Gene Information

• Gene Name: MPO myeloperoxidase [ Homo sapiens ]
• Official Symbol: MPO
• Synonyms: MPO; myeloperoxidase
• Gene ID: 4353
• mRNA Refseq: NM_000250
• Protein Refseq: NP_000241
• MIM: 606989
• UniProt ID: P05164
• Chromosome Location: 17q21.3-q23
• Pathway: C-MYB transcription factor network, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; IL23-mediated signaling events, organism-specific biosystem; Phagosome, organism-specific biosystem; Phagosome, conserved biosystem; Selenium Pathway, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem
• Function: chromatin binding; heme binding; heparin binding; metal ion binding; oxidoreductase activity; peroxidase activity

Reviews

08/12/2022

The technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.

05/05/2022

The MPO proteins purchased from your company is suitable for WB.

01/03/2021

Big company with guaranteed after-sales service., customers buy with confidence.

Q&As

Where is the MPO synthesized?

MPO is synthesized and stored by granulocytes in the bone marrow.

What biological processes are MPO involved in?

MPO mediates the production of halogenated oxidants in phagosomes and plays a key role in bacterial killing and protecting the body from disease.

What is the relationship of MPO to hypochlorous acid?

Under physiological conditions in the body, MPO catalyzes the production of hypochlorous acid.

What diseases can MPO be used as a marker for?

MPO can be used as a marker for cerebral stroke.

What diseases is MPO relevant to research?

MPO has been associated with studies of diseases such as leukemia and coronary heart disease.