Recombinant Human MPO Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | MPO-4004H |
Product Overview : | MPO MS Standard C13 and N15-labeled recombinant protein (NP_000241) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 83.7 kDa |
AA Sequence : | MGVPFFSSLRCMVDLGPCWAGGLTA EMKLLLALAGLLAILATPQPSEGAA PAVLGEVDTSLVLSSMEEAKQLVDK AYKERRESIKQRLRSGSASPMELLS YFKQPVAATRTAVRAADYLHVALDL LERKLRSLWRRPFNVTDVLTPAQLN VLSKSSGCAYQDVGVTCPEQDKYRT ITGMCNNRRSPTLGASNRAFVRWLP AEYEDGFSLPYGWTPGVKRNGFPVA LARAVSNEIVRFPTDQLTPDQERSL MFMQWGQLLDHDLDFTPEPAARASF VTGVNCETSCVQQPPCFPLKIPPND PRIKNQADCIPFFRSCPACPGSNIT IRNQINALTSFVDASMVYGSEEPLA RNLRNMSNQLGLLAVNQRFQDNGRA LLPFDNLHDDPCLLTNRSARIPCFL AGDTRSSEMPELTSMHTLLLREHNR LATELKSLNPRWDGERLYQEARKIV GAMVQIITYRDYLPLVLGPTAMRKY LPTYRSYNDSVDPRIANVFTNAFRY GHTLIQPFMFRLDNRYQPMEPNPRV PLSRVFFASWRVVLEGGIDPILRGL MATPAKLNRQNQIAVDEIRERLFEQ VMRIGLDLPALNMQRSRDHGLPGYN AWRRFCGLPQPETVGQLGTVLRNLK LARKLMEQYGTPNNIDIWMGGVSEP LKRKGRVGPLLACIIGTQFRKLRDG DRFWWENEGVFSMQQRQALAQISLP RIICDNTGITTVSKNNIFMSNSYPR DFVNCSTLPALNLASWREASTRTRP LEQKLISEEDLAANDILDYKDDDDK V |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | MPO myeloperoxidase [ Homo sapiens (human) ] |
Official Symbol : | MPO |
Synonyms : | MPO; myeloperoxidase; myeloperoxidase; EC 1.11.2.2 |
Gene ID : | 4353 |
mRNA Refseq : | NM_000250 |
Protein Refseq : | NP_000241 |
MIM : | 606989 |
UniProt ID : | P05164 |
Products Types
◆ Recombinant Protein | ||
Mpo-1790R | Recombinant Rat Mpo Protein, His-tagged | +Inquiry |
Mpo-4123M | Recombinant Mouse Mpo Protein, Myc/DDK-tagged | +Inquiry |
Mpo-52M | Recombinant Mouse Mpo Protein, His-tagged | +Inquiry |
MPO-5506H | Recombinant Human MPO Protein, GST-tagged | +Inquiry |
MPO-527H | Recombinant Human MPO Protein (Met1-Ser745), His-tagged | +Inquiry |
◆ Native Protein | ||
MPO-01H | Active Native Human MPO Protein | +Inquiry |
MPO -27H | Active Native Human Myeloperoxidase | +Inquiry |
MPO-8220H | Native Human Neutrophil Myeloperoxidase | +Inquiry |
◆ Lysates | ||
MPO-4234HCL | Recombinant Human MPO 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2293 | Myeloperoxidase (MPO) Fluorometric Activity Assay Kit | +Inquiry |
Kit-0607 | Myeloperoxidase Peroxidation Fluorometric Assay Kit | +Inquiry |
Kit-2292 | Myeloperoxidase (MPO) Colorimetric Activity Assay Kit | +Inquiry |
Kit-0604 | MPO Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMPO is synthesized and stored by granulocytes in the bone marrow.
MPO mediates the production of halogenated oxidants in phagosomes and plays a key role in bacterial killing and protecting the body from disease.
Under physiological conditions in the body, MPO catalyzes the production of hypochlorous acid.
MPO can be used as a marker for cerebral stroke.
MPO has been associated with studies of diseases such as leukemia and coronary heart disease.
Customer Reviews (3)
Write a reviewThe technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.
The MPO proteins purchased from your company is suitable for WB.
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