Recombinant Human MSLN Protein (Glu296-Gly580), C-His tagged
Cat.No. : | MSLN-3874H |
Product Overview : | Recombinant human MSLN (Glu296-Gly580) fused with the C-terminal His tag was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
- Download
Description : | Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro. |
Source : | Mammalian cells |
Species : | Human |
Tag : | C-His |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 31.35 kDa |
Protein Length : | Glu296-Gly580 |
Purity : | >90% as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS or lyophilized from PBS. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | MSLN mesothelin [ Homo sapiens (human) ] |
Official Symbol : | MSLN |
Synonyms : | MSLN; mesothelin; CAK1; MPF; CAK1 antigen; megakaryocyte potentiating factor; soluble MPF mesothelin related protein; pre-pro-megakaryocyte-potentiating factor; SMRP; |
Gene ID : | 10232 |
mRNA Refseq : | NM_001177355 |
Protein Refseq : | NP_001170826 |
MIM : | 601051 |
UniProt ID : | Q13421 |
Products Types
◆ Recombinant Protein | ||
MSLN-5659H | Recombinant Human MSLN Protein, GST-tagged | +Inquiry |
MSLN-384H | Recombinant Human MSLN Protein, His-tagged | +Inquiry |
MSLN-491H | Recombinant Human MSLN protein(Glu296-Gly580) | +Inquiry |
MSLN-25C | Recombinant Cynomolgus MSLN Protein, Fc tagged | +Inquiry |
MSLN-5745M | Recombinant Mouse MSLN Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
MSLN-1316HCL | Recombinant Human MSLN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionMSLN is normally expressed in mesothelial cells, playing a role in cell adhesion.
In cancer, MSLN expression is significantly upregulated.
MSLN is overexpressed in mesothelioma, ovarian, and pancreatic cancers.
Therapies targeting MSLN include antibody-drug conjugates and CAR-T cell therapies.
MSLN levels can be assessed through immunohistochemistry and serum biomarker tests.
MSLN overexpression is often associated with poor prognosis in cancer patients.
MSLN promotes tumor cell proliferation, invasion, and resistance to apoptosis.
Customer Reviews (3)
Write a reviewVery satisfied, great product.
Product is high-quality.
Excellent for experiments, reliable.
Ask a Question for All MSLN Products
Required fields are marked with *
My Review for All MSLN Products
Required fields are marked with *
Inquiry Basket