Recombinant Human MSLN Protein (Glu296-Gly580), C-mFc and 6×His-tagged
Cat.No. : | MSLN-651H |
Product Overview : | Recombinant Human MSLN Protein (Glu296-Gly580) with C-mFc and 6×His tag was expressed in HEK293. |
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Description : | This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
Source : | HEK293 |
Species : | Human |
Tag : | C-mFc and 6×His |
Form : | Lyophilized |
Molecular Mass : | 59.3 kDa |
Protein Length : | Glu296-Gly580 |
Purity : | > 95% as determined by SDS-PAGE and Coomassie blue staining. |
Storage : | Store at -80 centigrade for 12 months (Avoid repeated freezing and thawing) |
Storage Buffer : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 38 % trehalose is added as protectants before lyophilization. |
Gene Name : | MSLN mesothelin [ Homo sapiens (human) ] |
Official Symbol : | MSLN |
Synonyms : | MSLN; mesothelin; CAK1; MPF; CAK1 antigen; megakaryocyte potentiating factor; soluble MPF mesothelin related protein; pre-pro-megakaryocyte-potentiating factor; SMRP; |
Gene ID : | 10232 |
mRNA Refseq : | NM_001177355 |
Protein Refseq : | NP_001170826 |
MIM : | 601051 |
UniProt ID : | Q13421 |
Products Types
◆ Recombinant Protein | ||
MSLN-382H | Recombinant Human MSLN Protein, His-tagged | +Inquiry |
MSLN-3297H | Recombinant Human MSLN protein(Glu296-Gly580), His-tagged | +Inquiry |
MSLN-09H | Recombinant Human MSLN Protein, C-6His-Avi tagged, Biotinylated | +Inquiry |
MSLN-001H | Active Recombinant Human MSLN Protein, His-tagged | +Inquiry |
MSLN-381H | Recombinant Human MSLN Protein, His-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
MSLN-1343HCL | Recombinant Human MSLN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionMSLN is normally expressed in mesothelial cells, playing a role in cell adhesion.
In cancer, MSLN expression is significantly upregulated.
MSLN is overexpressed in mesothelioma, ovarian, and pancreatic cancers.
Therapies targeting MSLN include antibody-drug conjugates and CAR-T cell therapies.
MSLN levels can be assessed through immunohistochemistry and serum biomarker tests.
MSLN overexpression is often associated with poor prognosis in cancer patients.
MSLN promotes tumor cell proliferation, invasion, and resistance to apoptosis.
Customer Reviews (3)
Write a reviewVery satisfied, great product.
Product is high-quality.
Excellent for experiments, reliable.
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