Recombinant Human MSX2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MSX2-6143H
• Product Overview: MSX2 MS Standard C13 and N15-labeled recombinant protein (NP_002440) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 28.9 kDa
• AA Sequence: MASPSKGNDLFSPDEEGPAVVAGPG PGPGGAEGAAEERRVKVSSLPFSVE ALMSDKKPPKEASPLPAESASAGAT LRPLLLSGHGAREAHSPGPLVKPFE TASVKSENSEDGAAWMQEPGRYSPP PRHTSPTTCTLRKHKTNRKPRTPFT TSQLLALERKFRQKQYLSIAERAEF SSSLNLTETQVKIWFQNRRAKAKRL QEAELEKLKMAAKPMLPSSFSLPFP ISSPLQAASIYGASYPFHRPVLPIP PVGLYATPVGYGMYHLSTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MSX2 msh homeobox 2 [ Homo sapiens (human) ]
• Official Symbol: MSX2
• Synonyms: MSX2; msh homeobox 2; msh (Drosophila) homeo box homolog 2, msh homeobox homolog 2 (Drosophila), parietal foramina 1, PFM1; homeobox protein MSX-2; craniosynostosis; type 2; CRS2; FPP; HOX8; MSH; PFM; msh homeo box 2; homeobox protein Hox-8; msh homeobox homolog 2; PFM1
• Gene ID: 4488
• mRNA Refseq: NM_002449
• Protein Refseq: NP_002440
• MIM: 123101
• UniProt ID: P35548