Recombinant Human MUC16 protein, Fc-Avi-tagged, Biotinylated
Cat.No. : | MUC16-2978H |
Product Overview : | Biotinylated Recombinant Human MUC16 protein(Pro 13810-Pro 14451), fused with Fc and Avi tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | Fc-Avi |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. |
Molecular Mass : | This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™).The protein has a calculated MW of 100.0 kDa. The protein migrates as 120-160 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein Length : | Pro 13810-Pro 14451 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at-20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after storage at:-20°C to-70°C for 12 months in lyophilized state;-70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | MUC16 mucin 16, cell surface associated [ Homo sapiens ] |
Official Symbol : | MUC16 |
Synonyms : | MUC16; mucin 16, cell surface associated; mucin-16; CA125; FLJ14303; CA-125; MUC-16; CA125 ovarian cancer antigen; ovarian carcinoma antigen CA125; ovarian cancer-related tumor marker CA125; |
Gene ID : | 94025 |
mRNA Refseq : | NM_024690 |
Protein Refseq : | NP_078966 |
MIM : | 606154 |
UniProt ID : | Q8WXI7 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionMUC16 works with other mucins and immune components to maintain epithelial barrier function and immune responses.
It aids in forming the mucosal barrier, protecting against pathogens and mechanical damage.
Targeting MUC16 in cancer therapy, especially in ovarian cancer, could be effective in inhibiting tumor growth and spread.
Altered MUC16 activity can impact the body's defense against inflammation and infection.
MUC16, a mucin protein, is essential for maintaining the protective mucous layer on epithelial surfaces.
MUC16 is associated with cancer progression, particularly in ovarian cancer, where it may facilitate tumor growth and metastasis.
Genetic variations in MUC16 can lead to differences in mucosal integrity and potentially influence cancer susceptibility.
Customer Reviews (3)
Write a reviewCritical for decision-making. Supports our research endeavors.
Expert service quality. Valuable for research integrity.
Dependable partner in experiments. Consistent and trustworthy.
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