Recombinant Human MVK
Cat.No. : | MVK-26958TH |
Product Overview : | Recombinant fragment of Human MVK with an N terminal proprietary tag; Predicted MWt 36.63 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene. |
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | LIDMNQHHLNALGVGHASLDQLCQV TRARGLHSKLTGAGGGGCGITLLKP GLEQPEVEATKQALTSCGFDCLETS IGAPGVSIHSATSLDSRVQQALDGL |
Sequence Similarities : | Belongs to the GHMP kinase family. Mevalonate kinase subfamily. |
Gene Name : | MVK mevalonate kinase [ Homo sapiens ] |
Official Symbol : | MVK |
Synonyms : | MVK; mevalonate kinase; mevalonate kinase (mevalonic aciduria); LH receptor mRNA binding protein; LRBP; mevalonic aciduria; MK; |
Gene ID : | 4598 |
mRNA Refseq : | NM_000431 |
Protein Refseq : | NP_000422 |
MIM : | 251170 |
Uniprot ID : | Q03426 |
Chromosome Location : | 12q24 |
Pathway : | C5 isoprenoid biosynthesis, mevalonate pathway, organism-specific biosystem; C5 isoprenoid biosynthesis, mevalonate pathway, conserved biosystem; Cholesterol Biosynthesis, organism-specific biosystem; Cholesterol biosynthesis, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; |
Function : | ATP binding; identical protein binding; mevalonate kinase activity; mevalonate kinase activity; nucleotide binding; |
Products Types
◆ Recombinant Protein | ||
MVK-3487R | Recombinant Rat MVK Protein, His (Fc)-Avi-tagged | +Inquiry |
MVK-0262H | Recombinant Human MVK Protein (M1-L396), Tag Free | +Inquiry |
MVK-5819M | Recombinant Mouse MVK Protein, His (Fc)-Avi-tagged | +Inquiry |
MVK-2335H | Recombinant Human MVK Protein, MYC/DDK-tagged | +Inquiry |
MVK-0263H | Recombinant Human MVK Protein (M1-L396), His/Strep tagged | +Inquiry |
◆ Lysates | ||
MVK-001HCL | Recombinant Human MVK cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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