Recombinant Human MYBPC2 Protein (739-1141 aa), His-tagged

• Cat.No.: MYBPC2-1652H
• Product Overview: Recombinant Human MYBPC2 Protein (739-1141 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Partial.

Specification

• Description: Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
• Source: Yeast
• Species: Human
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 47.5 kDa
• Protein length: 739-1141 aa
• AA Sequence: EPLHLIVEDVTDTTTTLKWRPPNRI GAGGIDGYLVEYCLEGSEEWVPANT EPVERCGFTVKNLPTGARILFRVVG VNIAGRSEPATLAQPVTIREIAEPP KIRLPRHLRQTYIRKVGEQLNLVVP FQGKPRPQVVWTKGGAPLDTSRVHV RTSDFDTVFFVRQAARSDSGEYELS VQIENMKDTATIRIRVVEKAGPPIN VMVKEVWGTNALVEWQAPKDDGNSE IMGYFVQKADKKTMEWFNVYERNRH TSCTVSDLIVGNEYYFRVYTENICG LSDSPGVSKNTARILKTGITFKPFE YKEHDFRMAPKFLTPLIDRVVVAGY SAALNCAVRGHPKPKVVWMKNKMEI REDPKFLITNYQGVLTLNIRRPSPF DAGTYTCRAVNELGEALAECKLEVR VPQ
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: MYBPC2 myosin binding protein C, fast type [ Homo sapiens (human) ]
• Official Symbol: MYBPC2
• Synonyms: MYBPC; MYBPCF
• Gene ID: 4606
• mRNA Refseq: NM_004533
• Protein Refseq: NP_004524
• UniProt ID: Q14324