Recombinant Human MYD88 Protein (M157-P296), Tag Free
Cat.No. : | MYD88-0071H |
Product Overview : | Recombinant Human Myd88(M157-P296 end) Protein was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. Upon TLR8 activation by GU-rich single-stranded RNA (GU-rich RNA) derived from viruses such as SARS-CoV-2, SARS-CoV and HIV-1, induces IL1B release through NLRP3 inflammasome activation. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine. |
Source : | E. coli |
Species : | Human |
Tag : | No tag |
Form : | Liquid |
Protein Length : | M157-P296 |
Endotoxin : | < 0.01 EU per μg of the protein |
Purity : | 90% |
Stability : | Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied as sterile 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol |
Shipping : | It is shipped out with blue ice. |
Gene Name : | MYD88 myeloid differentiation primary response gene (88) [ Homo sapiens (human) ] |
Official Symbol : | MYD88 |
Synonyms : | MYD88; myeloid differentiation primary response gene (88); myeloid differentiation primary response protein MyD88; MYD88D; |
Gene ID : | 4615 |
mRNA Refseq : | NM_001172566 |
Protein Refseq : | NP_001166037 |
MIM : | 602170 |
UniProt ID : | Q99836 |
Products Types
◆ Recombinant Protein | ||
MYD88-3502R | Recombinant Rat MYD88 Protein, His (Fc)-Avi-tagged | +Inquiry |
MYD88-5796H | Recombinant Human MYD88 Protein, GST-tagged | +Inquiry |
MYD88-5835M | Recombinant Mouse MYD88 Protein, His (Fc)-Avi-tagged | +Inquiry |
MYD88-272H | Recombinant Human MYD88 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
MYD88-1147C | Recombinant Chicken MYD88 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
MYD88-4034HCL | Recombinant Human MYD88 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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