| Description : |
Striated muscle in vertebrates comprises large proteins which must be organized properly to contract efficiently. Z-lines in striated muscle are a sign of this organization, representing the ends of actin thin filaments, titin, nebulin or nebulette and accessory proteins required for structure and function. This gene encodes a protein which interacts with nebulin in skeletal muscle or nebulette in cardiac muscle and alpha-actinin. In addition, this gene product can interact with a protein with the I-band indicating it has a regulatory as well as structural function. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
145.1 kDa |
| AA Sequence : |
MQDDSIEASTSISQLLRESYLAETR HRGNNERSRAEPSSNPCHFGSPSGA AEGGGGQDDLPDLSAFLSQEELDES VNLARLAINYDPLEKADETQARKRL SPDQMKHSPNLSFEPNFCQDNPRSP TSSKESPQEAKRPQYCSETQSKKVF LNKAADFIEELSSLFKSHSSKRIRP RACKNHKSKLESQNKVMQENSSSFS DLSERRERSSVPIPIPADTRDNEVN HALEQQEAKRREAEQAASEAAGGDT TPGSSPSSLYYEEPLGQPPRFTQKL RSREVPEGTRVQLDCIVVGIPPPQV RWYCEGKELENSPDIHIVQAGNLHS LTIAEAFEEDTGRYSCFASNIYGTD STSAEIYIEGVSSSDSEGDPNKEEM NRIQKPNEVSSPPTTSAVIPPAVPQ AQHLVAQPRVATIQQCQSPTNYLQG LDGKPIIAAPVFTKMLQNLSASEGQ LVVFECRVKGAPSPKVEWYREGTLI EDSPDFRILQKKPRSMAEPEEICTL VIAEVFAEDSGCFTCTASNKYGTVS SIAQLHVRGNEDLSNNGSLHSANST TNLAAIEPQPSPPHSEPPSVEQPPK PKLEGVLVNHNEPRSSSRIGLRVHF NLPEDDKGSEASSEAGVVTTRQTRP DSFQERFNGQATKTPEPSSPVKEPP PVLAKPKLDSTQLQQLHNQVLLEQH QLQNPPPSSPKEFPFNMTVLNSNAP PAVTTSNKQVKAPSSQTFSLARPKY FFPSTNTTAATVAPSSSPVFTLSST PQTIQRTVSKESLLVSHPSVQTKSP GGLSIQNEPLPPGPTEPTPPPFTFS IPRGNQFQPRCVSPIPVSPTSRIQN PVAFLSSVLPSLPAIPPTNAMGLPR SAPSMPSQGLAKKNTKSPQPVNDDN IRETKNAVIRDLGKKITFSDVRPNQ QEYKISSFEQRLMNEIEFRLERTPV DESDDEIQHDEIPTGKCIAPIFDKR LKHFRVTEGSPVTFTCKIVGIPVPK VYWFKDGKQISKRNEHCKMRREGDG TCSLHIESTTSDDDGNYTIMAANPQ GRISCSGHLMVQSLPIRSRLTSAGQ SHRGRSRVQERDKEPLQERFFRPHF LQAPGDMVAHEGRLCRLDCKVSGLP PPELTWLLNGQPVLPDASHKMLVRE TGVHSLLIDPLTQRDAGTYKCIATN KTGQNSFSLELSVVAKEVKKAPVIL EKLQNCGVPEGHPVRLECRVIGMPP PVFYWKKDNETIPCTRERISMHQDT TGYACLLIQPAKKSDAGWYTLSAKN EAGIVSCTARLDIYAQWHHQIPPPM SVRPSGSRYGSLTSKGLDIFSAFSS MESTMVYSCSSRSVVESDELTRTRP LEQKLISEEDLAANDILDYKDDDDK V |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
