Recombinant Human NCF1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NCF1-2411H
• Product Overview: NCF1 MS Standard C13 and N15-labeled recombinant protein (NP_000256) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 44.5 kDa
• AA Sequence: MGDTFIRHIALLGFEKRFVPSQHYV YMFLVKWQDLSEKVVYRRFTEIYEF HKTLKEMFPIEAGAINPENRIIPHL PAPKWFDGQRAAENRQGTLTEYCST LMSLPTKISRCPHLLDFFKVRPDDL KLPTDNQTKKPETYLMPKDGKSTAT DITGPIILQTYRAIANYEKTSGSEM ALSTGDVVEVVEKSESGWWFCQMKA KRGWIPASFLEPLDSPDETEDPEPN YAGEPYVAIKAYTAVEGDEVSLLEG EAVEVIHKLLDGWWVIRKDDVTGYF PSMYLQKSGQDVSQAQRQIKRGAPP RRSSIRNAHSIHQRSRKRLSQDAYR RNSVRFLQQRRRQARPGPQSPGSPL EEERQTQRSKPQPAVPPRPSADLIL NRCSESTKRKLASPVTRTRPLEQKL ISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NCF1 neutrophil cytosolic factor 1 [ Homo sapiens (human) ]
• Official Symbol: NCF1
• Synonyms: NCF1; neutrophil cytosolic factor 1; neutrophil cytosolic factor 1 (47kD, chronic granulomatous disease, autosomal 1); neutrophil cytosol factor 1; chronic granulomatous disease; autosomal 1; NADPH oxidase organizer 2; NCF1A; NOXO2; p47phox; SH3PXD1A; NCF-1; NCF-47K; p47-phox; nox organizer 2; nox-organizing protein 2; 47 kDa neutrophil oxidase factor; neutrophil NADPH oxidase factor 1; SH3 and PX domain-containing protein 1A; 47 kDa autosomal chronic granulomatous disease protein; neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1); FLJ79451
• Gene ID: 653361
• mRNA Refseq: NM_000265
• Protein Refseq: NP_000256
• MIM: 608512
• UniProt ID: P14598