Recombinant Human NCF2 Protein, His-tagged

• Cat.No.: NCF2-400H
• Product Overview: Recombinant Human NCF2(Lys355~Val526) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 23.5kDa
• Identity: Reconstitute in PBS or others
• Protein length: Lys355~Val526
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: NCF2 neutrophil cytosolic factor 2 [ Homo sapiens ]
• Official Symbol: NCF2
• Synonyms: NCF2; neutrophil cytosolic factor 2; neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2); neutrophil cytosol factor 2; chronic granulomatous disease; autosomal 2; NADPH oxidase activator 2; NOXA2; p67phox; 67 kDa neutrophil oxidase factor; neutrophil NADPH oxidase factor 2; chronic granulomatous disease, autosomal 2; NCF-2; P67PHOX; P67-PHOX; FLJ93058
• Gene ID: 4688
• mRNA Refseq: NM_000433
• Protein Refseq: NP_000424
• MIM: 608515
• UniProt ID: P19878