Recombinant Human NDRG1 protein, GST-tagged

• Cat.No.: NDRG1-3770H
• Product Overview: Recombinant Human NDRG1 protein(45-109 aa), fused to GST tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: GST
• Form: The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8.). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 100mM GSH.
• Protein length: 45-109 aa
• AA Sequence: SGSSVTSLDGTRSRSHTSEGTRSRS HTSEGTRSRSHTSEGAHLDITPNSG AAGNSAGPKSMEVSC
• Purity: 95%, by SDS-PAGE with Coomassie Brilliant Blue staining.
• Storage: Short-term storage: Store at 2-8°C for (1-2 weeks).
  Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
• Reconstitution: Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
  Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.

Gene Information

• Gene Name: NDRG1 N-myc downstream regulated 1 [ Homo sapiens ]
• Official Symbol: NDRG1
• Synonyms: NDRG1; N-myc downstream regulated 1; CAP43; protein NDRG1; DRG1; NDR1; RTP; TDD5; DRG-1; protein regulated by oxygen-1; tunicamycin-responsive protein; differentiation-related gene 1 protein; nickel-specific induction protein Cap43; N-myc downstream-regulated gene 1 protein; reducing agents and tunicamycin-responsive protein; GC4; NMSL; CMT4D; HMSNL; RIT42; TARG1; PROXY1
• Gene ID: 10397
• mRNA Refseq: NM_001135242
• Protein Refseq: NP_001128714
• MIM: 605262
• UniProt ID: Q92597

Reviews

11/22/2020

Their expertise and assistance have been invaluable in troubleshooting and providing insightful solutions, greatly enhancing the progress of my experiments.

08/26/2020

They have proven to be a timely and reliable resource, readily addressing any concerns or challenges that arise during my research.

06/05/2018

The NDRG1 Protein's superior stability and functional performance render it an indispensable tool for a wide range of scientific investigations.

Q&As

Can NDRG1 be targeted for personalized medicine approaches?

Yes, understanding the individual's NDRG1 expression profile may enable personalized treatment strategies, especially in cancer therapy.

Are there therapeutic implications for modulating NDRG1 expression in cancer treatment?

Are there therapeutic implications for modulating NDRG1 expression in cancer treatment?

Are there clinical trials investigating the use of NDRG1-related therapies?

Yes, there are ongoing clinical trials exploring the safety and efficacy of NDRG1-targeted therapies in various diseases, reflecting the growing interest in its clinical applications.

How does NDRG1 contribute to cellular stress response?

NDRG1 is involved in cellular responses to various stresses, including oxidative stress and DNA damage, playing a role in maintaining cellular homeostasis.

How does NDRG1 affect cardiovascular health?

NDRG1 is involved in processes related to cardiac hypertrophy and response to ischemic stress, making it relevant to cardiovascular diseases.