Recombinant Human NDUFV2, His-tagged
Cat.No. : | NDUFV2-2313H |
Product Overview : | Recombinant human NDUFV2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. NDUFV2 is the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson"s disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT |
Molecular Mass : | 26.1 kDa |
Protein length : | 240aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSGAGGALF VHRDTPENNP DTPFDFTPEN YKRIEAIVKN YPEGHKAAAV LPVLDLAQRQ NGWLPISAMN KVAEVLQVPP MRVYEVATFY TMYNRKPVGK YHIQVCTTTP CMLRNSDSIL EAIQKKLGIK VGETTPDKLF TLIEVECLGA CVNAPMVQIN DNYYEDLTAK DIEEIIDELK AGKIPKPGPR SGRFSCEPAG GLTSLTEPPK GPGFGVQAGL |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml |
Gene Name : | NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa [ Homo sapiens ] |
Official Symbol : | NDUFV2 |
Synonyms : | NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa; NADH dehydrogenase (ubiquinone) flavoprotein 2 (24kD); NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; CI 24k; complex I 24kDa subunit; NADH dehydrogenase [ubiquinone] flavoprotein 2; mitochondrial; NADH-ubiquinone oxidoreductase 24 kDa subunit; NADH-ubiquinone oxidoreductase flavoprotein 2; complex I, mitochondrial respitory chain, 24 kD subunit; NADH dehydrogenase ubiquinone flavoprotein 2, mitochondrial; nuclear-encoded mitochondrial NADH-ubiquinone reductase 24Kd subunit; CI-24k; |
Gene ID : | 4729 |
mRNA Refseq : | NM_021074 |
Protein Refseq : | NP_066552 |
MIM : | 600532 |
UniProt ID : | P19404 |
Chromosome Location : | 18p11.22 |
Pathway : | Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Electron Transport Chain, organism-specific biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; |
Function : | 2 iron, 2 sulfur cluster binding; NAD binding; NADH dehydrogenase (ubiquinone) activity; NADH dehydrogenase (ubiquinone) activity; NADH dehydrogenase activity; electron carrier activity; metal ion binding; oxidoreductase activity; |
Products Types
◆ Recombinant Protein | ||
NDUFV2-2811R | Recombinant Rhesus Macaque NDUFV2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NDUFV2-3604R | Recombinant Rat NDUFV2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NDUFV2-5995M | Recombinant Mouse NDUFV2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ndufv2-4349M | Recombinant Mouse Ndufv2 Protein, Myc/DDK-tagged | +Inquiry |
NDUFV2-1244H | Recombinant Human NDUFV2, His-tagged | +Inquiry |
◆ Lysates | ||
NDUFV2-3891HCL | Recombinant Human NDUFV2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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