Recombinant Human NEFL Protein, His-tagged
Cat.No. : | NEFL-2484H |
Product Overview : | Recombinant Human NEFL Protein (Lys281-Glu396) with a N-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. |
Source : | E. coli |
Species : | Human |
Tag : | N-His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 17.0 kDa Accurate Molecular Mass: \ |
Protein length : | Lys281-Glu396 |
Endotoxin : | <1.0 EU per 1µg (determined by the LAL method). |
Purity : | > 90% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | NEFL neurofilament, light polypeptide [ Homo sapiens (human) ] |
Official Symbol : | NEFL |
Synonyms : | NEFL; neurofilament, light polypeptide; neurofilament, light polypeptide 68kDa; neurofilament light polypeptide; CMT1F; CMT2E; NF68; NFL; neurofilament subunit NF-L; neurofilament triplet L protein; neurofilament protein, light chain; light molecular weight neurofilament protein; NF-L; FLJ53642; |
Gene ID : | 4747 |
mRNA Refseq : | NM_006158 |
Protein Refseq : | NP_006149 |
MIM : | 162280 |
UniProt ID : | P07196 |
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NEFL-3610R | Recombinant Rat NEFL Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
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NEFL-181B | Native bovine NEFL | +Inquiry |
◆ Lysates | ||
NEFL-3884HCL | Recombinant Human NEFL 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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