Recombinant Human NEIL2 Protein, MYC/DDK-tagged, C13 and N15-labeled
Cat.No. : | NEIL2-351H |
Product Overview : | NEIL2 MS Standard C13 and N15-labeled recombinant protein (NP_659480) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the Fpg/Nei family of DNA glycosylases. These glycosylases initiate the first step in base excision repair by cleaving oxidatively damaged bases and introducing a DNA strand break via their abasic site lyase activity. This enzyme is primarily associated with DNA repair during transcription and acts prefentially on cytosine-derived lesions, particularly 5-hydroxyuracil and 5-hydroxycytosine. It contains an N-terminal catalytic domain, a hinge region, and a C-terminal DNA-binding domain with helix-two-turn-helix and zinc finger motifs. This enzyme interacts with the X-ray cross complementing factor 1 scaffold protein as part of a multi-protein DNA repair complex. A pseudogene of this gene has been identified. [provided by RefSeq, Mar 2017] |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 36.8 kDa |
AA Sequence : | MPEGPLVRKFHHLVSPFVGQQVVKT GGSSKKLQPASLQSLWLQDTQVHGK KLFLRFDLDEEMGPPGSSPTPEPPQ KEVQKEGAADPKQVGEPSGQKTLDG SSRSAELVPQGEDDSEYLERDAPAG DAGRWLRVSFGLFGSVWVNDFSRAK KANKRGDWRDPSPRLVLHFGGGGFL AFYNCQLSWSSSPVVTPTCDILSEK FHRGQALEALGQAQPVCYTLLDQRY FSGLGNIIKNEALYRAGIHPLSLGS VLSASRREVLVDHVVEFSTAWLQGK FQGRPQHTQVYQKEQCPAGHQVMKE AFGPEDGLQRLTWWCPQCQPQLSEE PEQCQFSTRTRPLEQKLISEEDLAA NDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | NEIL2 nei endonuclease VIII-like 2 (E. coli) [ Homo sapiens (human) ] |
Official Symbol : | NEIL2 |
Synonyms : | NEIL2; nei endonuclease VIII-like 2 (E. coli); nei like 2 (E. coli); endonuclease 8-like 2; FLJ31644; MGC2832; MGC4505; NEH2; nei like 2; nei homolog 2; nei-like protein 2; endonuclease VIII-like 2; DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; NEI2; |
Gene ID : | 252969 |
mRNA Refseq : | NM_145043 |
Protein Refseq : | NP_659480 |
MIM : | 608933 |
UniProt ID : | Q969S2 |
Products Types
◆ Recombinant Protein | ||
Neil2-4366M | Recombinant Mouse Neil2 Protein, Myc/DDK-tagged | +Inquiry |
NEIL2-15866H | Recombinant Human NEIL2, His-tagged | +Inquiry |
NEIL2-3048H | Recombinant Human NEIL2 protein, His-tagged | +Inquiry |
NEIL2-2042H | Recombinant Human Nei Endonuclease VIII-like 2 (E. coli) | +Inquiry |
NEIL2-5185C | Recombinant Chicken NEIL2 | +Inquiry |
◆ Lysates | ||
NEIL2-3881HCL | Recombinant Human NEIL2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket