Recombinant Human NEK2
Cat.No. : | NEK2-29279TH |
Product Overview : | Recombinant full length NEK2 protein (Human), was expressed by baculovirus in Sf9 insect cells using a N-terminal tag, MW 76kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene. |
Tissue specificity : | Isoform 1 and isoform 2 are expressed in peripheral blood T-cells and a wide variety of transformed cell types. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.Contains 1 protein kinase domain. |
Gene Name : | NEK2 NIMA (never in mitosis gene a)-related kinase 2 [ Homo sapiens ] |
Official Symbol : | NEK2 |
Synonyms : | NEK2; NIMA (never in mitosis gene a)-related kinase 2; serine/threonine-protein kinase Nek2; HsPK 21; NEK2A; NLK1; |
Gene ID : | 4751 |
mRNA Refseq : | NM_001204182 |
Protein Refseq : | NP_001191111 |
MIM : | 604043 |
Uniprot ID : | P51955 |
Chromosome Location : | 1q32-q42 |
Pathway : | Cell Cycle, Mitotic, organism-specific biosystem; Centrosome maturation, organism-specific biosystem; FOXM1 transcription factor network, organism-specific biosystem; G2/M Transition, organism-specific biosystem; Loss of Nlp from mitotic centrosomes, organism-specific biosystem; |
Function : | ATP binding; metal ion binding; nucleotide binding; protein binding; protein kinase activity; |
Products Types
◆ Recombinant Protein | ||
NEK2-0906H | Recombinant Human NEK2 Protein (1-271, T175A), His tagged | +Inquiry |
NEK2-788H | Recombinant Human NEK2 Protein, His-tagged | +Inquiry |
Nek2-789M | Recombinant Mouse Nek2 Protein, His-tagged | +Inquiry |
NEK2-2817R | Recombinant Rhesus Macaque NEK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NEK2-0905H | Recombinant Human NEK2 Protein (1-271, T175A), Tag Free | +Inquiry |
◆ Lysates | ||
NEK2-1183HCL | Recombinant Human NEK2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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