Recombinant Human NEUROD1 Protein, His-tagged

• Cat.No.: NEUROD1-07H
• Product Overview: Recombinant human NeuroD1 (Thr2-Asp356) with a N-terminal 6x histidine tag was derived from E.coli

Specification

• Description: This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized powder
• Molecular Mass: 37 kDa
• Protein length: 2-356
• Purity: > 85%
• Applications: Protein-protein Interaction, Post-translational Modifications, ELISA, EIA, WB, DB, IP, Protein Array, etc.
• Storage: Upon arrival, the lyophilized protein may be stored for 2 weeks at 4 centigrade. For long term storage, it is recommended to store desiccated below -20 centigrade in a manual defrost freezer. Following reconstitution, the protein may be stored for 2 weeks under sterile conditions at -20 centigrade. For long term storage, it is recommended to make appropriate aliquots and store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Lyophilized from a 0.45 μm filtered solution in 1x PBS (pH 7.4).
• Reconstitution: Briefly spin the vial and bring the contents to the bottom prior to opening. It is recommended to reconstitute at 0.5~1.0 mg/mL with sterile deionized water.
• Shipping: Ice packs

Gene Information

• Gene Name: NEUROD1 neuronal differentiation 1 [ Homo sapiens (human) ]
• Official Symbol: NEUROD1
• Synonyms: NEUROD1; neuronal differentiation 1; T2D; BETA2; BHF-1; MODY6; NEUROD; bHLHa3; neurogenic differentiation factor 1; basic helix-loop-helix transcription factor; beta-cell E-box transactivator 2; class A basic helix-loop-helix protein 3; neurogenic helix-loop-helix protein NEUROD
• Gene ID: 4760
• mRNA Refseq: NM_002500
• Protein Refseq: NP_002491
• MIM: 601724
• UniProt ID: Q13562