Recombinant Human Neutrophil Cytosolic Factor 1, His-tagged
Cat.No. : | NCF1-1721H |
Product Overview : | Recombinant humanNCF1 protein, fused to His-tag at C-terminus, was expressed in E. coli andpurified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | NCF1-1721H |
Description : | Neutrophil cytosolicfactor 1, also known as NCF1, is a cytosolic subunit of neutrophil NADPHoxidase. NCF1, along with NCF2 and a membrane bound cytochrome b558, isrequired for activation of the latent NADPH oxidase necessary for superoxideproduction. Defects in NCF1, often resulting from recombination between NCF1and a nearby homologous pseudogene, cause chronic granulomatous disease. |
Concentration : | 0.5 mg/ml |
Source : | Human |
Host : | E. coli |
Form : | Supplied as a liquidin 20 mM Tris-HCl buffer, pH 8.0, containing 1 mM DTT, 20% glycerol and 0.1 MNaCl. |
Purity : | > 90% pure bySDS-PAGE |
Sequence : | 1-390 amino acids:MGDTFIRHIA LLGFEKRFVP SQHYVYMFLV KWQDLSEKVV YRRFTEIYEF HKTLKEMFPI EAGAINPENRIIPHLPAPKW FDGQRAAENR QGTLTEYCST LMSLPTKISR CPHLLDFFKV RPDDLKLPTD NQTKKPETYLMPKDGKSTAT DITGPIILQT YRAIANYEKT SGSEMALSTG DVVEVVEKSE SGWWFCQMKA KRGWIPASFLEPLD |
Molecular Mass : | 45.7 kDa (398 aa)confirmed by MALDI-TOF |
Applications : | SDS-PAGE |
Storage : | Store at 4 deg C forshort term storage (1/2 weeks). Aliquot and store at -20 deg C or -70 deg Cfor long term storage. Avoid repeated freeze/thaw cycles. |
OfficialSymbol : | NCF1 |
Gene Name : | NCF1neutrophil cytosolic factor 1 [ Homo sapiens ] |
Synonyms : | NCF1; neutrophil cytosolic factor 1;NCF1A; NOXO2; p47phox; FLJ79451; SH3PXD1A; NCF-1; NCF-47K; p47-phox; nox organizer 2; OTTHUMP00000195569; nox-organizing protein 2; NADPH oxidase organizer 2; 47 kDa neutrophil oxidase factor; neutrophil NADPH oxidase factor 1; SH3 and PX domain-containing protein 1A; 47 kDa autosomal chronic granulomatous disease protein; neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) |
Gene ID : | 653361 |
mRNA Refseq : | NM_000265 |
Protein Refseq : | NP_000256 |
MIM : | 608512 |
UniProt ID : | P14598 |
Chromosome Location : | 7q11.23 |
Pathway : | Chemokine signalingpathway; Fc gamma R-mediated phagocytosis; Leishmaniasis; Leukocyte transendothelial migration; Osteoclastdifferentiation; Phagosome; RAC1 signaling pathway |
Function : | superoxide-generatingNADPH oxidase activity; protein binding; phosphatidylinositol binding;electron carrier activity; SH3 domain binding; GTPase activity; GTP binding |
Products Types
◆ Recombinant Protein | ||
NCF1-1485H | Recombinant Human NCF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ncf1-4308M | Recombinant Mouse Ncf1 Protein, Myc/DDK-tagged | +Inquiry |
NCF1-5937M | Recombinant Mouse NCF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NCF1-2411C | Recombinant Chicken NCF1 | +Inquiry |
NCF1-1208H | Recombinant Human NCF1, His-tagged | +Inquiry |
◆ Lysates | ||
NCF1-3950HCL | Recombinant Human NCF1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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