Recombinant Human NFASC Protein, C-Myc/DDK-tagged
Cat.No. : | NFASC-12H |
Product Overview : | Purified recombinant protein of Homo sapiens neurofascin (NFASC), transcript variant 1 with C-Myc/DDK-tag was expressed in HEK293T. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined. |
Source : | HEK293T |
Species : | Human |
Tag : | C-Myc/DDK |
Molecular Mass : | 135 kDa |
AA Sequence : | MARQPPPPWVHAAFLLCLLSLGGAI EIPMDPSIQNELTQPPTITKQSAKD HIVDPRDNILIECEAKGNPAPSFHW TRNSRFFNIAKDPRVSMRRRSGTLV IDFRSGGRPEEYEGEYQCFARNKFG TALSNRIRLQVSKSPLWPKENLDPV VVQEGAPLTLQCNPPPGLPSPVIFW MSSSMEPITQDKRVSQGHNGDLYFS NVMLQDMQTDYSCNARFHFTHTIQQ KNPFTLKVLTTRGVAERTPSFMYPQ GTASSQMVLRGMDLLLECIASGVPT PDIAWYKKGGDLPSDKAKFENFNKA LRITNVSEEDSGEYFCLASNKMGSI RHTISVRVKAAPYWLDEPKNLILAP GEDGRLVCRANGNPKPTVQWMVNGE PLQSAPPNPNREVAGDTIIFRDTQI SSRAVYQCNTSNEHGYLLANAFVSV LDVPPRMLSPRNQLIRVILYNRTRL DCPFFGSPIPTLRWFKNGQGSNLDG GNYHVYENGSLEIKMIRKEDQGIYT CVATNILGKAENQVRLEVKDPTRIY RMPEDQVARRGTTVQLECRVKHDPS LKLTVSWLKDDEPLYIGNRMKKEDD SLTIFGVAERDQGSYTCVASTELDQ DLAKAYLTVLADQATPTNRLAALPK GRPDRPRDLELTDLAERSVRLTWIP GDANNSPITDYVVQFEEDQFQPGVW HDHSKYPGSVNSAVLRLSPYVNYQF RVIAINEVGSSHPSLPSERYRTSGA PPESNPGDVKGEGTRKNNMEITWTP MNATSAFGPNLRYIVKWRRRETREA WNNVTVWGSRYVVGQTPVYVPYEIR VQAENDFGKGPEPESVIGYSGEDLP SAPRRFRVRQPNLETINLEWDHPEH PNGIMIGYTLKYVAFNGTKVGKQIV ENFSPNQTKFTVQRTDPVSRYRFTL SARTQVGSGEAVTEESPAPPNEATP TAAPPTLPPTTVGATGAVSSTDATA IAATTEATTVPIIPTVAPTTIATTT TVATTTTTTAAATTTTESPPTTTSG TKIHESAPDEQSIWNVTVLPNSKWA NITWKHNFGPGTDFVVEYIDSNHTK KTVPVKAQAQPIQLTDLYPGMTYTL RVYSRDNEGISSTVITFMTSTAYTN NQADIATQGWFIGLMCAIALLVLIL LIVCFIKRSRGGKYPVREKKDVPLG PEDPKEEDGSFDYSDEDNKPLQGSQ TSLDGTIKQQESDDSLVDYGEGGEG QFNEDGSFIGQYTVKKDKEETEGNE SSEATSPVNAIYSLATRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Gene Name : | NFASC neurofascin [ Homo sapiens (human) ] |
Official Symbol : | NFASC |
Synonyms : | NFASC; neurofascin; NF; NRCAML; NEDCPMD; neurofascin; neurofascin homolog |
Gene ID : | 23114 |
mRNA Refseq : | NM_001005388 |
Protein Refseq : | NP_001005388 |
MIM : | 609145 |
UniProt ID : | O94856 |
Products Types
◆ Recombinant Protein | ||
NFASC-621H | Recombinant Human NFASC Protein (Met1-Gln939), HIgG1 Fc-tagged, Biotinylated | +Inquiry |
NFASC-596H | Recombinant Human NFASC Protein, GST-tagged | +Inquiry |
NFASC-2489H | Recombinant Human NFASC protein(1241-1330 aa), C-His-tagged | +Inquiry |
NFASC-3627R | Recombinant Rat NFASC Protein, His (Fc)-Avi-tagged | +Inquiry |
Nfasc-4386M | Recombinant Mouse Nfasc Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
NFASC-918HCL | Recombinant Human NFASC cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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