Recombinant Human NFE2L2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NFE2L2-4685H
• Product Overview: NFE2L2 MS Standard C13 and N15-labeled recombinant protein (NP_006155) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 67.8 kDa
• AA Sequence: MMDLELPPPGLPSQQDMDLIDILWR QDIDLGVSREVFDFSQRRKEYELEK QKKLEKERQEQLQKEQEKAFFAQLQ LDEETGEFLPIQPAQHIQSETSGSA NYSQVAHIPKSDALYFDDCMQLLAQ TFPFVDDNEVSSATFQSLVPDIPGH IESPVFIATNQAQSPETSVAQVAPV DLDGMQQDIEQVWEELLSIPELQCL NIENDKLVETTMVPSPEAKLTEVDN YHFYSSIPSMEKEVGNCSPHFLNAF EDSFSSILSTEDPNQLTVNSLNSDA TVNTDFGDEFYSAFIAEPSISNSMP SPATLSHSLSELLNGPIDVSDLSLC KAFNQNHPESTAEFNDSDSGISLNT SPSVASPEHSVESSSYGDTLLGLSD SEVEELDSAPGSVKQNGPKTPVHSS GDMVQPLSPSQGQSTHVHDAQCENT PEKELPVSPGHRKTPFTKDKHSSRL EAHLTRDELRAKALHIPFPVEKIIN LPVVDFNEMMSKEQFNEAQLALIRD IRRRGKNKVAAQNCRKRKLENIVEL EQDLDHLKDEKEKLLKEKGENDKSL HLLKKQLSTLYLEVFSMLRDEDGKP YSPSEYSLQQTRDGNVFLVPKSKKP DVKKNTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NFE2L2 nuclear factor, erythroid 2 like 2 [ Homo sapiens (human) ]
• Official Symbol: NFE2L2
• Synonyms: NFE2L2; nuclear factor (erythroid-derived 2)-like 2; nuclear factor erythroid 2-related factor 2; NF E2 related factor 2; NRF2; HEBP1; NFE2-related factor 2; NF-E2-related factor 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid derived 2, like 2
• Gene ID: 4780
• mRNA Refseq: NM_006164
• Protein Refseq: NP_006155
• MIM: 600492
• UniProt ID: Q16236