Recombinant Human NLGN4X Protein, His-tagged

• Cat.No.: NLGN4X-34H
• Product Overview: Recombinant human NLGN4X protein with a His-tag was expressed in HEK293

Specification

• Description: This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: His
• Molecular Mass: The protein has a calculated MW of 73 kDa.
• AA Sequence: QYPVVNTNYGKIRGLRTPLPNEILG PVEQYLGVPYASPPTGERRFQPPEP PSSWTGIRNTTQFAAVCPQHLDERS LLHDMLPIWFTANLDTLMTYVQDQN EDCLYLNIYVPTEDDIHDQNSKKPV MVYIHGGSYMEGTGNMIDGSILASY GNVIVITINYRLGILGFLSTGDQAA KGNYGLLDQIQALRWIEENVGAFGG DPKRVTIFGSGAGASCVSLLTLSHY SEGLFQKAIIQSGTALSSWAVNYQP AKYTRILADKVGCNMLDTTDMVECL RNKNYKELIQQTITPATYHIAFGPV IDGDVIPDDPQILMEQGEFLNYDIM LGVNQGEGLKFVDGIVDNEDGVTPN DFDFSVSNFVDNLYGYPEGKDTLRE TIKFMYTDWADKENPETRRKTLVAL FTDHQWVAPAVATADLHAQYGSPTY FYAFYHHCQSEMKPSWADSAHGDEV PYVFGIPMIGPTELFSCNFSKNDVM LSAVVMTYWTNFAKTGDPNQPVPQD TKFIHTKPNRFEEVAWSKYNPKDQL YLHIGLKPRVRDHYRATKVAFWLEL VPHLHNLNEIFQYVSTTTKVPPPDM TSFPYGTRRSPAKIWPTTKRPAITP ANNPKHSKDPHKTGPEDTTVLIETK RDYSTELGGGSGGGSHHHHHHHHHH
• Purity: >90% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.2 mg/mL
• Storage Buffer: PBS pH7.4

Gene Information

• Gene Name: NLGN4X neuroligin 4, X-linked [ Homo sapiens (human) ]
• Official Symbol: NLGN4X
• Synonyms: NLGN4X; neuroligin 4, X-linked; neuroligin 4 , NLGN4; neuroligin-4, X-linked; HLNX; KIAA1260; NLGN; neuroligin X; HNLX; HNL4X; NLGN4; ASPGX2; AUTSX2; MGC22376
• Gene ID: 57502
• mRNA Refseq: NM_020742
• Protein Refseq: NP_065793
• MIM: 300427
• UniProt ID: Q8N0W4