Recombinant Human NLRC5 protein, His-tagged

• Cat.No.: NLRC5-489H
• Product Overview: Recombinant Human NLRC5 fused with His tag was expressed in HEK293.

Specification

• Description: This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways.
• Source: HEK293
• Species: Human
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Purity: >90% ( SDS-PAGE )
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: Store at -20 centigrade, for extended storage, conserve at -20 centigrade or -80 centigrade.

Gene Information

• Gene Name: NLRC5 NLR family, CARD domain containing 5 [ Homo sapiens ]
• Official Symbol: NLRC5
• Synonyms: NLRC5; NLR family, CARD domain containing 5; protein NLRC5; CLR16.1; FLJ21709; NOD like receptor C5; NOD27; nucleotide binding oligomerization domain; leucine rich repeat and CARD domain containing 5; NOD-like receptor C5; caterpiller protein 16.1; nucleotide-binding oligomerization domains 27; nucleotide-binding oligomerization domain protein 4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 5; NOD4; FLJ39711
• Gene ID: 84166
• mRNA Refseq: NM_032206
• Protein Refseq: NP_115582
• MIM: 613537
• UniProt ID: Q86WI3
• Chromosome Location: 16q13
• Pathway: Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Negative regulators of RIG-I/MDA5 signaling, organism-specific biosystem; RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways, organism-specific biosystem
• Function: ATP binding; RNA polymerase II core promoter sequence-specific DNA binding; nucleotide binding; protein binding