| Description : |
This gene encodes a member of the non-metastatic expressed family of nucleoside diphosphate kinases. Members of this family are enzymes that catalyzes phosphate transfer from nucleoside triphosphates to nucleoside diphosphates. This protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
42.5 kDa |
| AA Sequence : |
MNHSERFVFIAEWYDPNASLLRRYE LLFYPGDGSVEMHDVKNHRTFLKRT KYDNLHLEDLFIGNKVNVFSRQLVL IDYGDQYTARQLGSRKEKTLALIKP DAISKAGEIIEIINKAGFTITKLKM MMLSRKEALDFHVDHQSRPFFNELI QFITTGPIIAMEILRDDAICEWKRL LGPANSGVARTDASESIRALFGTDG IRNAAHGPDSFASAAREMELFFPSS GGCGPANTAKFTNCTCCIVKPHAVS EGLLGKILMAIRDAGFEISAMQMFN MDRVNVEEFYEVYKGVVTEYHDMVT EMYSGPCVAMEIQQNNATKTFREFC GPADPEIARHLRPGTLRAIFGKTKI QNAVHCTDLPEDGLLEVQYFFKILD NTRTRPLEQKLISEEDLAANDILDY KDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
