Recombinant Human NME8 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NME8-5884H
• Product Overview: TXNDC3 MS Standard C13 and N15-labeled recombinant protein (NP_057700) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 67.3 kDa
• AA Sequence: MASKKREVQLQTVINNQSLWDEMLQ NKGLTVIDVYQAWCGPCRAMQPLFR KLKNELNEDEILHFAVAEADNIVTL QPFRDKCEPVFLFSVNGKIIEKIQG ANAPLVNKKVINLIDEERKIAAGEM ARPQYPEIPLVDSDSEVSEESPCES VQELYSIAIIKPDAVISKKVLEIKR KITKAGFIIEAEHKTVLTEEQVVNF YSRIADQRDFEEFVSFMTSGLSYIL VVSQGSKHNPPSEETEPQTDTEPNE RSEDQPEVEAQVTPGMMKNKQDSLQ EYLERQHLAQLCDIEEDAANVAKFM DAFFPDFKKMKSMKLEKTLALLRPN LFHERKDDVLRIIKDEDFKILEQRQ VVLSEKEAQALCKEYENEDYFNKLI ENMTSGPSLALVLLRDNGLQYWKQL LGPRTVEEAIEYFPESLCAQFAMDS LPVNQLYGSDSLETAEREIQHFFPL QSTLGLIKPHATSEQREQILKIVKE AGFDLTQVKKMFLTPEQTEKIYPKV TGKDFYKDLLEMLSVGPSMVMILTK WNAVAEWRRLMGPTDPEEAKLLSPD SIRAQFGISKLKNIVHGASNAYEAK EVVNRLFEDPEENTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NME8 NME/NM23 family member 8 [ Homo sapiens (human) ]
• Official Symbol: NME8
• Synonyms: NME8; NME/NM23 family member 8; CILD6; SPTRX2; TXNDC3; NM23-H8; sptrx-2; HEL-S-99; thioredoxin domain-containing protein 3; epididymis secretory protein Li 99; sperm-specific thioredoxin 2; spermatid-specific thioredoxin-2; thioredoxin domain containing 3 (spermatozoa)
• Gene ID: 51314
• mRNA Refseq: NM_016616
• Protein Refseq: NP_057700
• MIM: 607421
• UniProt ID: Q8N427