Recombinant Human NMI Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NMI-5682H
• Product Overview: NMI MS Standard C13 and N15-labeled recombinant protein (NP_004679) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 35.1 kDa
• AA Sequence: MEADKDDTQQILKEHSPDEFIKDEQ NKGLIDEITKKNIQLKKEIQKLETE LQEATKEFQIKEDIPETKMKFLSVE TPENDSQLSNISCSFQVSSKVPYEI QKGQALITFEKEEVAQNVVSMSKHH VQIKDVNLEVTAKPVPLNSGVRFQV YVEVSKMKINVTEIPDTLREDQMRD KLELSFSKSRNGGGEVDRVDYDRQS GSAVITFVEIGVADKILKKKEYPLY INQTCHRVTVSPYTEIHLKKYQIFS GTSKRTVLLTGMEGIQMDEEIVEDL INIHFQRAKNGGGEVDVVKCSLGQP HIAYFEETRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NMI N-myc and STAT interactor [ Homo sapiens (human) ]
• Official Symbol: NMI
• Synonyms: NMI; N-myc (and STAT) interactor; N-myc-interactor; N-myc interactor
• Gene ID: 9111
• mRNA Refseq: NM_004688
• Protein Refseq: NP_004679
• MIM: 603525
• UniProt ID: Q13287