Recombinant Human NOS1AP Protein (Thr285-Val506), His tagged

• Cat.No.: NOS1AP-2716H
• Product Overview: Recombinant human NOS1AP (Thr285-Val506) protein fused with His tag was expressed in E. coli.

Specification

• Description: Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 26.16 kDa
• Protein Length: Thr285-Val506
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein [ Homo sapiens (human) ]
• Official Symbol: NOS1AP
• Synonyms: NOS1AP; nitric oxide synthase 1 (neuronal) adaptor protein; carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein; C terminal PDZ domain ligand of neuronal nitric oxide synthase; CAPON; KIAA0464; nitric oxide synthase 1 adaptor protein; C-terminal PDZ ligand of neuronal nitric oxide synthase protein; C-terminal PDZ domain ligand of neuronal nitric oxide synthase (CAPON); ligand of neuronal nitric oxide synthase with carboxyl-terminal PDZ domain; 6330408P19Rik; MGC138500
• Gene ID: 9722
• mRNA Refseq: NM_001126060
• Protein Refseq: NP_001119532
• MIM: 605551
• UniProt ID: O75052