| Description : |
This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
53.4 kDa |
| AA Sequence : |
MEEHGVTQTEHMATIEAHAVAQQVQ QVHVATYTEHSMLSADEDSPSSPED TSYDDSDILNSTAADEVTAHLAAAG PVGMAAAAAVATGKKRKRPHVFESN PSIRKRQQTRLLRKLRATLDEYTTR VGQQAIVLCISPSKPNPVFKVFGAA PLENVVRKYKSMILEDLESALAEHA PAPQEVNSELPPLTIDGIPVSVDKM TQAQLRAFIPEMLKYSTGRGKPGWG KESCKPIWWPEDIPWANVRSDVRTE EQKQRVSWTQALRTIVKNCYKQHGR EDLLYAFEDQQTQTQATATHSIAHL VPSQTVVQTFSNPDGTVSLIQVGTG ATVATLADASELPTTVTVAQVNYSA VADGEVEQNWATLQGGEMTIQTTQA SEATQAVASLAEAAVAASQEMQQGA TVTMALNSEAAAHAVATLAEATLQG GGQIVLSGETAAAVGALTGVQDANG LVQIPVSMYQTVVTSLAQGNGPVQV AMAPVTTRISDSAVTMDGQAVEVVT LEQTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
