Active Recombinant Human NRP1 protein, His-Avi-tagged, Biotinylated

• Cat.No.: NRP1-8119H
• Product Overview: Biotinylated Recombinant Human NRP1 protein(Phe 22 - Lys 644), fused with His and Avi tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
• Bio-activity: Immobilized Human VEGF165, premium grade at 2 μg/mL (100 μL/well) can bind Biotinylated Human Neuropilin-1, His,Avitag with a linear range of 0.5-16 ng/mL.
• Molecular Mass: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag)The protein has a calculated MW of 73.5 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Protein Length: Phe 22 - Lys 644
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at:
  -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: NRP1 neuropilin 1 [ Homo sapiens ]
• Official Symbol: NRP1
• Synonyms: NRP1; neuropilin 1; neuropilin-1; CD304; NRP; VEGF165R; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; NP1; BDCA4; DKFZp781F1414; DKFZp686A03134
• Gene ID: 8829
• mRNA Refseq: NM_001024628
• Protein Refseq: NP_001019799
• MIM: 602069
• UniProt ID: O14786

Reviews

05/24/2022

The protein has a moderate molecular weight and is convenient to use.

07/12/2021

NRP1 can be easily used and measured in experiment.

04/20/2021

NRP1 has a high purity.

Q&As

What is the role of NRP1 in lung disease?

It may be involved in the processes of angiography, inflammation, fibrosis and other processes in the lungs, and is related to the occurrence and development of lung diseases.

What factors are associated with high NRP1 expression?

The high expression of NRP1 may be related to factors such as the aggressiveness of the tumor and the increased angiogenesis of the tumor.

Can NRP1 be targeted for targeted therapy?

Yes, NRP1, as a molecule with important biological functions and clinical significance, can be targeted as a target therapy.

What are the applications of NRP1 in clinical diagnosis?

This protein can be used as a potential marker in clinical diagnosis for tumor diagnosis and prognosis evaluation.

Is NRP1 associated with drug therapy?

Yes, NRP1 may be related to the metabolism of drugs, the response to drug treatment, etc., which affects the efficacy and side effects of drugs.

How is NRP1 related to immune diseases?

NRP1 may be involved in the regulation of autoimmune responses, inflammatory responses, etc., and is related to the occurrence and development of immune diseases.