| Description : |
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
45 kDa |
| Protein Length : |
822 |
| AA Sequence : |
MSSWIRWHGPAMARLWGFCWLVVGF WRAAFACPTSCKCSASRIWCSDPSP GIVAFPRLEPNSVDPENITEIFIAN QKRLEIINEDDVEAYVGLRNLTIVD SGLKFVAHKAFLKNSNLQHINFTRN KLTSLSRKHFRHLDLSELILVGNPF TCSCDIMWIKTLQEAKSSPDTQDLY CLNESSKNIPLANLQIPNCGLPSAN LAAPNLTVEEGKSITLSCSVAGDPV PNMYWDVGNLVSKHMNETSHTQGSL RITNISSDDSGKQISCVAENLVGED QDSVNLTVHFAPTITFLESPTSDHH WCIPFTVKGNPKPALQWFYNGAILN ESKYICTKIHVTNHTEYHGCLQLDN PTHMNNGDYTLIAKNEYGKDEKQIS AHFMGWPGIDDGANPNYPDVIYEDY GTAANDIGDTTNRSNEIPSTDVTDK TGREHLSVYAVVVIASVVGFCLLVM LFLLKLARHSKFGMKGPASVISNDD DSASPLHHISNGSNTPSSSEGGPDA VIIGMTKIPVIENPQYFGITNSQLK PDTFVQHIKRHNIVLKRELGEGAFG KVFLAECYNLCPEQDKILVAVKTLK DASDNARKDFHREAELLTNLQHEHI VKFYGVCVEGDPLIMVFEYMKHGDL NKFLRAHGPDAVLMAEGNPPTELTQ SQMLHIAQQIAAGMVYLASQHFVHR DLATRNCLVGENLLVKIGDFGMSRD VYSTDYYRVGGHTMLPIRWMPPESI MYRKFTTESDVWSLGVVLWEIFTYG KQPWYQLSNNEVIECITQGRVLQRP RTCPQEVYELMLGCWQREPHMRKNI KGIHTLLQNLAKASPVYLDILG |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
