| Description : |
Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
155 kDa |
| AA Sequence : |
MPSSLLGAAMPASTSAAALQEALEN AGRLIDRQLQEDRMYPDLSELLMVS APNNPTVSGMSDMDYPLQGPGLLSV PNLPEISSIRRVPLPPELVEQFGHM QCNCMMGVFPPISRAWLTIDSDIFM WNYEDGGDLAYFDGLSETILAVGLV KPKAGIFQPHVRHLLVLATPVDIVI LGLSYANLQTGSGVLNDSLSGGMQL LPDPLYSLPTDNTYLLTITSTDNGR IFLAGKDGCLYEVAYQAEAGWFSQR CRKINHSKSSLSFLVPSLLQFTFSE DDPILQIAIDNSRNILYTRSEKGVI QVYDLGQDGQGMSRVASVSQNAIVS AAGNIARTIDRSVFKPIVQIAVIEN SESLDCQLLAVTHAGVRLYFSTCPF RQPLARPNTLTLVHVRLPPGFSASS TVEKPSKVHRALYSKGILLMAASEN EDNDILWCVNHDTFPFQKPMMETQM TAGVDGHSWALSAIDELKVDKIITP LNKDHIPITDSPVVVQQHMLPPKKF VLLSAQGSLMFHKLRPVDQLRHLLV SNVGGDGEEIERFFKLHQEDQACAT CLILACSTAACDREVSAWATRAFFR YGGEAQMRFPTTLPPPSNVGPILGS PVYSSSPVPSGSPYPNPSFLGTPSH GIQPPAMSTPVCALGNPATQATNMS CVTGPEIVYSGKHNGICIYFSRIMG NIWDASLVVERIFKSGNREITAIES SVPCQLLESVLQELKGLQEFLDRNS QFAGGPLGNPNTTAKVQQRLIGFMR PENGNPQQMQQELQRKFHEAQLSEK ISLQAIQQLVRKSYQALALWKLLCE HQFTIIVAELQKELQEQLKITTFKD LVIRDKELTGALIASLINCYIRDNA AVDGISLHLQDICPLLYSTDDAICS KANELLQRSRQVQNKTEKERMLRES LKEYQKISNQVDLSNVCAQYRQVRF YEGVVELSLTAAEKKDPQGLGLHFY KHGEPEEDIVGLQAFQERLNSYKCI TDTLQELVNQSKAAPQSPSVPKKPG PPVLSSDPNMLSNEEAGHHFEQMLK LSQRSKDELFSIALYNWLIQVDLAD KLLQVASPFLEPHLVRMAKVDQNRV RYMDLLWRYYEKNRSFSNAARVLSR LADMHSTEISLQQRLEYIARAILSA KSSTAISSIAADGEFLHELEEKMEV ARIQLQIQETLQRQYSHHSSVQDAV SQLDSELMDITKLYGEFADPFKLAE CKLAIIHCAGYSDPILVQTLWQDII EKELSDSVTLSSSDRMHALSLKIVL LGKIYAGTPRFFPLDFIVQFLEQQV CTLNWDVGFVIQTMNEIGVPLPRLL EVYDQLFKSRDPFWNRMKKPLHLLD CIHVLLIRYVENPSQVLNCERRRFT NLCLDAVCGYLVELQSMSSSVAVQA ITGNFKSLQAKLERLHTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
