| Description : |
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a membrane-spanning glycoprotein that is a major component of the nuclear pore complex. Multiple pseudogenes related to this gene are located on chromosome 3. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
204.9 kDa |
| AA Sequence : |
MAARGRGLLLLTLSVLLAAGPSAAA AKLNIPKVLLPFTRATRVNFTLEAS EGCYRWLSTRPEVASIEPLGLDEQQ CSQKAVVQARLTQPARLTSIIFAED ITTGQVLRCDAIVDLIHDIQIVSTT RELYLEDSPLELKIQALDSEGNTFS TLAGLVFEWTIVKDSEADRFSDSHN ALRILTFLESTYIPPSYISEMEKAA KQGDTILVSGMKTGSSKLKARIQEA VYKNVRPAEVRLLILENILLNPAYD VYLMVGTSIHYKVQKIRQGKITELS MPSDQYELQLQNSIPGPEGDPARPV AVLAQDTSMVTALQLGQSSLVLGHR SIRMQGASRLPNSTIYVVEPGYLGF TVHPGDRWVLETGRLYEITIEVFDK FSNKVYVSDNIRIETVLPAEFFEVL SSSQNGSYHRIRALKRGQTAIDAAL TSVVDQDGGVHILQVPVWNQQEVEI HIPITLYPSILTFPWQPKTGAYQYT IRAHGGSGNFSWSSSSHLVATVTVK GVMTTGSDIGFSVIQAHDVQNPLHF GEMKVYVIEPHSMEFAPCQVEARVG QALELPLRISGLMPGGASEVVTLSD CSHFDLAVEVENQGVFQPLPGRLPP GSEHCSGIRVKAEAQGSTTLLVSYR HGHVHLSAKITIAAYLPLKAVDPSS VALVTLGSSKEMLFEGGPRPWILEP SKFFQNVTAEDTDSIGLALFAPHSS RNYQQHWILVTCQALGEQVIALSVG NKPSLTNPFPAVEPAVVKFVCAPPS RLTLAPVYTSPQLDMSCPLLQQNKQ VVPVSSHRNPRLDLAAYDQEGRRFD NFSSLSIQWESTRPVLASIEPELPM QLVSQDDESGQKKLHGLQAILVHEA SGTTAITATATGYQESHLSSARTKQ PHDPLVPLSASIELILVEDVRVSPE EVTIYNHPGIQAELRIREGSGYFFL NTSTADVVKVAYQEARGVAMVHPLL PGSSTIMIHDLCLVFPAPAKAVVYV SDIQELYIRVVDKVEIGKTVKAYVR VLDLHKKPFLAKYFPFMDLKLRAAS PIITLVALDEALDNYTITFLIRGVA IGQTSLTASVTNKAGQRINSAPQQI EVFPPFRLMPRKVTLLIGATMQVTS EGGPQPQSNILFSISNESVALVSAA GLVQGLAIGNGTVSGLVQAVDAETG KVVIISQDLVQVEVLLLRAVRIRAP IMRMRTGTQMPIYVTGITNHQNPFS FGNAVPGLTFHWSVTKRDVLDLRGR HHEASIRLPSQYNFAMNVLGRVKGR TGLRVVVKAVDPTSGQLYGLARELS DEIQVQVFEKLQLLNPEIEAEQILM SPNSYIKLQTNRDGAASLSYRVLDG PEKVPVVHVDEKGFLASGSMIGTST IEVIAQEPFGANQTIIVAVKVSPVS YLRVSMSPVLHTQNKEALVAVPLGM TVTFTVHFHDNSGDVFHAHSSVLNF ATNRDDFVQIGKGPTNNTCVVRTVS VGLTLLRVWDAEHPGLSDFMPLPVL QAISPELSGAMVVGDVLCLATVLTS LEGLSGTWSSSANSILHIDPKTGVA VARAVGSVTVYYEVAGHLRTYKEVV VSVPQRIMARHLHPIQTSFQEATAS KVIVAVGDRSSNLRGECTPTQREVI QALHPETLISCQSQFKPAVFDFPSQ DVFTVEPQFDTALGQYFCSITMHRL TDKQRKHLSMKKTALVVSASLSSSH FSTEQVGAEVPFSPGLFADQAEILL SNHYTSSEIRVFGAPEVLENLEVKS GSPAVLAFAKEKSFGWPSFITYTVG VLDPAAGSQGPLSTTLTFSSPVTNQ AIAIPVTVAFVVDRRGPGPYGASLF QHFLDSYQVMFFTLFALLAGTAVMI IAYHTVCTPRDLAVPAALTPRASPG HSPHYFAASSPTSPNALPPARKASP PSGLWSPAYASHTRTRPLEQKLISE EDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
