| Description : |
This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
82.6 kDa |
| AA Sequence : |
MEDYPDPQSANHMNSSLLSLYRKGN PDSVSNTPEMEQRETTSSTPRISSK TGSIPLKTPAKDSEGGWFIDKTPSV KKDSFFLDLSCEKSNPKKPITEIQD SKDSSLLESDMKRKGKLKNKGSKRK KEDLQEVDGEIEAVLQKKAKARGLE FQISNVKFEDVGGNDMTLKEVCKML IHMRHPEVYHHLGVVPPRGVLLHGP PGCGKTLLAHAIAGELDLPILKVAA PEIVSGVSGESEQKLRELFEQAVSN APCIIFIDEIDAITPKREVASKDME RRIVAQLLTCMDDLNNVAATARVLV IGATNRPDSLDPALRRAGRFDREIC LGIPDEASRERILQTLCRKLRLPQA FDFCHLAHLTPGFVGADLMALCREA AMCAVNRVLMKLQEQQKKNPEMEDL PSKGVQEERLGTEPTSETQDELQRL LGLLRDQDPLSEEQMQGLCIELNDF IVALSSVQPSAKREGFVTVPNVTWA DIGALEDIREELTMAILAPVRNPDQ FKALGLVTPAGVLLAGPPGCGKTLL AKAVANESGLNFISVKGPELLNMYV GESERAVRQVFQRAKNSAPCVIFFD EVDALCPRRSDRETGASVRVVNQLL TEMDGLEARQQVFIMAATNRPDIID PAILRPGRLDKTLFVGLPPPADRLA ILKTITKNGTKPPLDADVNLEAIAG DLRCDCYTGADLSALVREASICALR QEMARQKSGNEKGELKVSHKHFEEA FKKVRSSISKKDQIMYERLQESLSR TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
