| Description : |
This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
115.5 kDa |
| AA Sequence : |
MASSVGNVADSTGLAELAHREYQAG DFEAAERHCMQLWRQEPDNTGVLLL LSSIHFQCRRLDRSAHFSTLAIKQN PLLAEAYSNLGNVYKERGQLQEAIE HYRHALRLKPDFIDGYINLAAALVA AGDMEGAVQAYVSALQYNPDLYCVR SDLGNLLKALGRLEEAKACYLKAIE TQPNFAVAWSNLGCVFNAQGEIWLA IHHFEKAVTLDPNFLDAYINLGNVL KEARIFDRAVAAYLRALSLSPNHAV VHGNLACVYYEQGLIDLAIDTYRRA IELQPHFPDAYCNLANALKEKGSVA EAEDCYNTALRLCPTHADSLNNLAN IKREQGNIEEAVRLYRKALEVFPEF AAAHSNLASVLQQQGKLQEALMHYK EAIRISPTFADAYSNMGNTLKEMQD VQGALQCYTRAIQINPAFADAHSNL ASIHKDSGNIPEAIASYRTALKLKP DFPDAYCNLAHCLQIVCDWTDYDER MKKLVSIVADQLEKNRLPSVHPHHS MLYPLSHGFRKAIAERHGNLCLDKI NVLHKPPYEHPKDLKLSDGRLRVGY VSSDFGNHPTSHLMQSIPGMHNPDK FEVFCYALSPDDGTNFRVKVMAEAN HFIDLSQIPCNGKAADRIHQDGIHI LVNMNGYTKGARNELFALRPAPIQA MWLGYPGTSGALFMDYIITDQETSP AEVAEQYSEKLAYMPHTFFIGDHAN MFPHLKKKAVIDFKSNGHIYDNRIV LNGIDLKAFLDSLPDVKIVKMKCPD GGDNADSSNTALNMPVIPMNTIAEA VIEMINRGQIQITINGFSISNGLAT TQINNKAATGEEVPRTIIVTTRSQY GLPEDAIVYCNFNQLYKIDPSTLQM WANILKRVPNSVLWLLRFPAVGEPN IQQYAQNMGLPQNRIIFSPVAPKEE HVRRGQLADVCLDTPLCNGHTTGMD VLWAGTPMVTMPGETLASRVAASQL TCLGCLELIAKNRQEYEDIAVKLGT DLEYLKKVRGKVWKQRISSPLFNTK QYTMELERLYLQMWEHYAAGNKPDH MIKPVEVTESASGPTRTRRLEQKLI SEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
