| Description : |
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
53.8 kDa |
| AA Sequence : |
MNGEEEFFDAVTEANQKVTGMIDLD TSKNNRIGKTGERPSQENGIQKHRT SLPAPMFSRSDFSVWTILKKCVGLE LSKITMPIAFNEPLSFLQRITEYME HVYLIHRASCQPQPLERMQSVAAFA VSAVASQWERTGKPFNPLLGETYEL IREDLGFRFISEQVSHHPPISAFHS EGLNHDFLFHGSIYPKLKFWGKSVE AEPRGTITLELLKHNEAYTWTNPTC CVHNVIIGKLWIEQYGTVEILNHRT GHKCVLHFKPCGLFGKELHKVEGHI QDKNKKKLFMIYGKWTECLWGIDPV SYESFKKQERRGDHLRKAKLDEDSG KADSDVADDVPVAQETVQVIPGSKL LWRINTRPPNSAQMYNFTSFTVSLN ELETGMEKTLPPTDCRLRPDIRGME NGNMDLASQEKERLEEKQREARRER AKEEAEWQTRWFYPGNNPYTGTPDW LYAGDYFERNFSDCPDIYTRTRPLE QKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
