Recombinant Human PAX8
Cat.No. : | PAX8-29058TH |
Product Overview : | Recombinant full length Human PAX8 with a proprietary tag: predicted molecular weight 75.24 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. |
Protein length : | 451 amino acids |
Molecular Weight : | 75.240kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Expressed in the excretory system, thyroid gland and Wilms tumors. |
Biological activity : | useful for Antibody Production and Protein Array |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Glutathione is reduced |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MPHNSIRSGHGGLNQLGGAFVNGRP LPEVVRQRIVDLAHQGVRPCDISRQ LRVSHGCVSKILGRYYETGSIRPGV IGGSKPKVATPKVVEKIGDYKRQNP TMFAWEIRDRLLAEGVCDNDTVPSV SSINRIIRTKVQQPFNLPMDSCVAT KSLSPGHTLIPSSAVTPPESPQSDS LGSTYSINGLLGIAQPGSDKRKMDD SDQDSCRLSIDSQSSSSGPRKHLRT DAFSQHHLEPLECPFERQHYPEAYA SPSHTKGEQGLYPLPLLNSTLDDGK ATLTPSNTPLGRNLSTHQTYPVVAD PHSPFAIKQETPEVSSSSSTPSSLS SSAFLDLQQVGSGVPPFNAFPHAAS VYGQFTGQALLSGREMVGPTLPGYP PHIPTSGQGSYASSAIAGMVAGSEY SGNAYGHTPYSSYSEAWRFPNSSLL SSPYYYSSTSRPSAPPTTATAFDHL |
Sequence Similarities : | Contains 1 paired domain. |
Gene Name : | PAX8 paired box 8 [ Homo sapiens ] |
Official Symbol : | PAX8 |
Synonyms : | PAX8; paired box 8; paired box gene 8; paired box protein Pax-8; |
Gene ID : | 7849 |
mRNA Refseq : | NM_003466 |
Protein Refseq : | NP_003457 |
MIM : | 167415 |
Uniprot ID : | Q06710 |
Chromosome Location : | 2q13 |
Pathway : | Id Signaling Pathway, organism-specific biosystem; Pathways in cancer, organism-specific biosystem; Thyroid cancer, organism-specific biosystem; Thyroid cancer, conserved biosystem; Transcriptional misregulation in cancers, organism-specific biosystem; |
Function : | DNA binding; DNA binding; RNA polymerase II core promoter sequence-specific DNA binding; protein binding; sequence-specific DNA binding; |
Products Types
◆ Recombinant Protein | ||
Pax8-4687M | Recombinant Mouse Pax8 Protein, Myc/DDK-tagged | +Inquiry |
PAX8-2552H | Recombinant Human PAX8 Protein, His-tagged | +Inquiry |
PAX8-1611H | Recombinant Human PAX8 Protein, His (Fc)-Avi-tagged | +Inquiry |
PAX8-59H | Recombinant Human PAX8 Protein, C-His tagged | +Inquiry |
PAX8-02H | Recombinant Human PAX8 Protein, C-Myc/DDK tagged | +Inquiry |
◆ Lysates | ||
PAX8-3412HCL | Recombinant Human PAX8 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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