| Description : |
This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
41.5 kDa |
| AA Sequence : |
MSGSDGGLEEEPELSITLTLRMLMH GKEVGSIIGKKGETVKRIREQSSAR ITISEGSCPERITTITGSTAAVFHA VSMIAFKLDEDLCAAPANGGNVSRP PVTLRLVIPASQCGSLIGKAGTKIK EIRETTGAQVQVAGDLLPNSTERAV TVSGVPDAIILCVRQICAVILESPP KGATIPYHPSLSLGTVLLSANQGFS VQGQYGAVTPAEVTKLQQLSSHAVP FATPSVVPGLDPGTQTSSQEFLVPN DLIGCVIGRQGSKISEIRQMSGAHI KIGNQAEGAGERHVTITGSPVSIAL AQYLITACLETAKSTSGGTPSSAPA DLPAPFSPPLTALPTAPPGLLGTPY AISLSNFIGLKPMPFLALPPASPGP PPGLAAYTAKMAAANGSKKAERQKF SPYTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
