| Description : |
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
113 kDa |
| AA Sequence : |
MSPVRRWGSPCLFPLQLFSLCWVLS VAQSKTVRYSTFEEDAPGTVIGTLA EDLHMKVSGDTSFRLMKQFNSSLLR VREGDGQLTVGDAGLDRERLCGQAP QCVLAFDVVSFSQEQFRLVHVEVEV RDVNDHAPRFPRAQIPVEVSEGAAV GTRIPLEVPVDEDVGANGLQTVRLA EPHSPFRVELQTRADGAQCADLVLL QELDRESQAAYSLELVAQDGGRPPR SATAALSVRVLDANDHSPAFPQGAV AEVELAEDAPVGSLLLDLDAADPDE GPNGDVVFAFGARTPPEARRLFRLD PRSGRLTLAGPVDYERQDTYELDVR AQDRGPGPRAATCKVIVRIRDVNDN APDIAITPLAAPGAPATSPFAAAAA AAALGGADASSPAGAGTPEAGATSL VPEGAARESLVALVSTSDRDSGANG QVRCALYGHEHFRLQPAYAGSYLVV TAASLDRERIAEYNLTLVAEDRGAP PLRTVRPYTVRVGDENDNAPLFTRP VYEVSVRENNPPGAYLATVAARDRD LGRNGQVTYRLLEAEVGRAGGAVST YVSVDPATGAIYALRSFDYETLRQL DVRIQASDGGSPQLSSSALVQVRVL DQNDHAPVLVHPAPANGSLEVAVPG RTAKDTVVARVQARDADEGANGELA FELQQQEPREAFAIGRRTGEILLTG DLSQEPPGRVFRALLVISDGGRPPL TTTATVSFVVTAGGGRGPAAPASAG SPERSRPPGSRLGVSGSVLQWDTPL IVIIVLAGSCTLLLAAIIAIATTCN RRKKEVRKGGALREERPGAAGGGAS APGSPEEAARGAGPRPNMFDVLTFP GTGKAPFGCPAADAPPPAVAAAEVP GSEGGSATGESACHFEGQQRLRGAH AEPYGASPGFGKEPAPPVAVWKGHS FNTISGREAEKFSGKDSGKGDSDFN DSDSDISGDALKKDLINHMQSGLWA CTAECKILGHSDRCWSPSCSGPNAH PSPHPPAQMSTFCKSTSLPRDPLRR DNYYQAQLPKTVGLQSVYEKVLHRD YDRTVTLLSPPRPGRLPDLQEIGVP LYQSPPGRYLSPKKGANENVTRTRP LEQKLISEEDLAANDILDYKDDDDK V |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
