Recombinant Human PDCD1 Protein (G22-V170), C-6×His tagged
Cat.No. : | PDCD1-75H |
Product Overview : | Recombinant human PD-1, extracellular domain is produced in E. coli. The final protein sequence contains G22-V170 of human PD1 fused to a polyhistidine tag on the carboxyl terminus. This product is sterile and does not contain any components of animal origin. |
- Specification
- Gene Information
- Related Products
Description : | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. |
Source : | E. coli |
Species : | Human |
Tag : | C-6×His |
Protein Length : | G22-V170 |
AA Sequence : | MPGWFLDSPDRPWNPPTFSPALLVV TEGDNATFTCSFSNTSESFVLNWYR MSPSNQTDKLAAFPEDRSQPGQDCR FRVTQLPNGRDFHMSVVRARRNDSG TYLCGAISLAPKAQIKESLRAELRV TERRAEVPTAHPSPSPRPAGQFQTL VGSHHHHHH |
Purity : | > 95% by SDS-PAGE |
Applications : | Research in immunotherapy |
Quality Control Test : | Verified by disulfide mapping and Mass Spectrometry analysis. |
Notes : | For research use only |
Storage : | Avoid repeated freeze-thaw cycles. 12 months at -20 to -80 centigrade. 1 month at 2 to 8 centigrade. |
Concentration : | 0.4 mg/mL |
Storage Buffer : | Sterile filtered through a 0.2 micron filter in 50% glycerol, 10 mM MES buffer at pH 6.5 |
Gene Name : | PDCD1 programmed cell death 1 [ Homo sapiens (human) ] |
Official Symbol : | PDCD1 |
Synonyms : | PDCD1; programmed cell death 1; programmed cell death protein 1; CD279; PD1; protein PD-1; PD-1; SLEB2; hPD-1; hPD-l |
Gene ID : | 5133 |
mRNA Refseq : | NM_005018 |
Protein Refseq : | NP_005009 |
MIM : | 600244 |
UniProt ID : | Q15116 |
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◆ Lysates | ||
PDCD1-001RCL | Recombinant Rat PDCD1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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