Recombinant Human PDCD1LG2 Protein (Leu20-Pro219), C-Fc tagged
Cat.No. : | PDCD1LG2-5190H |
Product Overview : | Recombinant human PDCD1LG2 (Leu20-Pro219) fused with the C-terminal Fc tag was expressed in mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
Source : | Mammalian cells |
Species : | Human |
Tag : | C-Fc |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 47 kDa |
Protein Length : | Leu20-Pro219 |
Purity : | >90% as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS or lyophilized from PBS. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | PDCD1LG2 programmed cell death 1 ligand 2 [ Homo sapiens (human) ] |
Official Symbol : | PDCD1LG2 |
Synonyms : | PDCD1LG2; programmed cell death 1 ligand 2; B7 dendritic cell molecule; B7 DC; bA574F11.2; Btdc; CD273; PD L2; PDL2; B7-DC; PD-1 ligand 2; PD-1-ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; programmed death ligand 2; B7DC; PD-L2; PDCD1L2; MGC142238; MGC142240; |
Gene ID : | 80380 |
mRNA Refseq : | NM_025239 |
Protein Refseq : | NP_079515 |
MIM : | 605723 |
UniProt ID : | Q9BQ51 |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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