Recombinant Human PDGFA Protein

• Cat.No.: PDGFA-32H
• Product Overview: Recombinant human PDGF-AA protein without tag was expressed in E. coli.
  Animal-free (AOF) and carrier protein-free.
  Mass spectrometry: single species with expected mass.
  Analytical reversed-phase: single sharp peak.
  Recovery from stock vial: >95%

Specification

• Description: This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Molecular Mass: 29 kDa
• Endotoxin: <0.005 EU/μg protein (below level of detection)
• Applications: Maturation of hepatoblasts into hepatocyte like cells
• Storage: Resuspend in water at >100 μg/mL, prepare single use aliquots, add carrier protein if desired and store frozen at -20 or -80 centigrade
• Storage Buffer: Lyophilized from acetonitrile, TFA

Gene Information

• Gene Name: PDGFA platelet derived growth factor subunit A [ Homo sapiens (human) ]
• Official Symbol: PDGFA
• Synonyms: PDGFA; platelet derived growth factor subunit A; PDGF1; PDGF-A; platelet-derived growth factor subunit A; PDGF A-chain; PDGF subunit A; platelet-derived growth factor A-chain; platelet-derived growth factor alpha chain; platelet-derived growth factor alpha polypeptide
• Gene ID: 5154
• mRNA Refseq: NM_033023
• Protein Refseq: NP_148983
• MIM: 173430
• UniProt ID: P04085