Recombinant Human PDGFRA, GST-tagged, Active
Cat.No. : | PDGFRA-384H |
Product Overview : | Recombinant full-length PDGFRA (550-end) was expressed bybaculovirusinSf9 insect cellsusing an N-terminal GST tag. MW=95kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PDGFRA-384H |
Description : | PDGFRα (platelet-derived growth factor receptor α) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. Aberrant expression of PDGFRα has been linked to developmental abnormalities in vertebrate models and has been implicated in multiple disease states in humans. There is widespread expression of PDGFRα in renal cell types involved in fibrotic and sclerosing processes. PDGF and its receptor PDGFRα are inducers of fibrosis in the repair phase of inflammatory bowel disease and they may also be involved in the active inflammatory phase. |
Source : | Sf9 insect cells using baculovirus. |
Sequence : | 550-end. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | PDGFRA platelet-derived growth factor receptor, alpha polypeptide [ Homo sapiens ] |
Synonyms : | PDGFRA; platelet-derived growth factor receptor, alpha polypeptide; CD140A; PDGFR2; MGC74795; RHEPDGFRA; Alpha-type platelet-derived growth factor receptor; EC 2.7.10.1; PDGF-R-alpha; CD140 antigen-like family member A; CD140a antigen |
Gene ID : | 5156 |
mRNA Refseq : | NM_006206 |
Protein Refseq : | NP_006197 |
MIM : | 173490 |
UniProt ID : | P16234 |
Chromosome Location : | 4q12 |
Pathway : | Calcium signaling pathway; Colorectal cancer; Cytokine-cytokine receptor interaction; Endocytosis; Focal adhesion; Gap junction; Glioma; Pathways in cancer; Regulation of actin cytoskeleton; Signaling by PDGF |
Function : | ATP binding; nucleotide binding; platelet-derived growth factor alpha-receptor activity; platelet-derived growth factor binding; platelet-derived growth factor receptor binding; protein heterodimerization activity; receptor activity; transferase activity; vascular endothelial growth factor receptor activity |
Products Types
◆ Recombinant Protein | ||
PDGFRA-2664H | Recombinant Human PDGFRA protein(961-1040 aa), C-His-tagged | +Inquiry |
Pdgfra-99M | Recombinant Mouse Pdgfra Protein, His (Fc)-Avi-tagged | +Inquiry |
PDGFRA-270H | Recombinant Human PDGFRA Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
PDGFRA-38H | Recombinant Active Human PDGFR alpha (E675G Y676C) Mutant Protein, GST-tagged | +Inquiry |
PDGFRA-1633H | Recombinant Human PDGFRA Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PDGFRA-001HCL | Recombinant Human PDGFRA cell lysate | +Inquiry |
PDGFRA-2657HCL | Recombinant Human PDGFRA cell lysate | +Inquiry |
PDGFRA-824RCL | Recombinant Rat PDGFRA cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1615 | PDGFRa Functional Assay Kit | +Inquiry |
Kit-1616 | U2OS PDGFRa Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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