Recombinant Human PDGFRA protein, His-tagged
Cat.No. : | PDGFRA-3181H |
Product Overview : | Recombinant Human PDGFRA (Gln24-Ala528) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
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Description : | PDGFRA(platelet-derived growth factor receptor A), also termed PDGFRα(platelet-derived growth factor receptor α), is a receptor located on the surface of a wide range of cell types. This receptor binds to certain isoforms of platelet-derived growth factors (PDGFs) and thereby becomes active in stimulating cell signaling pathways that elicit responses such as cellular growth and differentiation. The receptor is critical for the development of certain tissues and organs during embryogenesis and for the maintenance of these tissues and organs, particularly hematologic tissues, throughout life. Mutations in the gene which codes for PDGFRA, are associated with an array of clinically significant neoplasms. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Gln24 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 58.4 kDa. The protein migrates as 66-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Gln24-Ala528 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | PDGFRA |
Official Symbol : | PDGFRA |
Synonyms : | PDGFRA; platelet-derived growth factor receptor, alpha polypeptide; platelet-derived growth factor receptor alpha; CD140a; PDGFR2; PDGFR-alpha; PDGF-R-alpha; CD140a antigen; PDGFRA/BCR fusion; CD140 antigen-like family member A; platelet-derived growth factor receptor 2; alpha-type platelet-derived growth factor receptor; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; CD140A; PDGFR-2; RHEPDGFRA; MGC74795 |
Gene ID : | 5156 |
mRNA Refseq : | NM_006206 |
Protein Refseq : | NP_006197 |
MIM : | 173490 |
UniProt ID : | P16234 |
Products Types
◆ Recombinant Protein | ||
PDGFRA-37H | Recombinant Active Human PDGFR alpha (G680R) Mutant Protein, GST-tagged | +Inquiry |
PDGFRA-2664H | Recombinant Human PDGFRA protein(961-1040 aa), C-His-tagged | +Inquiry |
Pdgfra-4758M | Recombinant Mouse Pdgfra Protein, Myc/DDK-tagged | +Inquiry |
PDGFRA-2050H | Recombinant Human PDGFRA Protein, Fc/His-tagged | +Inquiry |
PDGFRA-38H | Recombinant Active Human PDGFR alpha (E675G Y676C) Mutant Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
PDGFRA-2657HCL | Recombinant Human PDGFRA cell lysate | +Inquiry |
PDGFRA-001HCL | Recombinant Human PDGFRA cell lysate | +Inquiry |
PDGFRA-824RCL | Recombinant Rat PDGFRA cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1615 | PDGFRa Functional Assay Kit | +Inquiry |
Kit-1616 | U2OS PDGFRa Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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