Recombinant Human PDGFRB Protein, Fc/His-tagged
Cat.No. : | PDGFRB-2058H |
Product Overview : | Recombinant Human PDGFRB/CD140b Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Leu33-Phe530 (Glu241Asp)) of human PDGFRB/CD140b (Accession #NP_002600.1) fused with an Fc, 6×His tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. |
Source : | HEK293 |
Species : | Human |
Tag : | Fc/His |
Form : | Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5 % mannitol. |
Protein length : | Leu33-Phe530 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | > 90% as determined by SDS-PAGE |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | PDGFRB platelet-derived growth factor receptor, beta polypeptide [ Homo sapiens ] |
Official Symbol : | PDGFRB |
Synonyms : | PDGFRB; platelet-derived growth factor receptor, beta polypeptide; PDGFR; platelet-derived growth factor receptor beta; CD140b; JTK12; PDGFR1; PDGFR-beta; PDGF-R-beta; CD140 antigen-like family member B; platelet-derived growth factor receptor 1; beta-type platelet-derived growth factor receptor; CD140B; PDGFR-1; |
Gene ID : | 5159 |
mRNA Refseq : | NM_002609 |
Protein Refseq : | NP_002600 |
MIM : | 173410 |
UniProt ID : | P09619 |
Products Types
◆ Recombinant Protein | ||
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PDGFRB-416H | Recombinant Human PDGFRB Protein, Fc-tagged | +Inquiry |
PDGFRB-271H | Recombinant Human PDGFRB Protein (ECD) (Glu241Asp), Fc-His-tagged(C-ter) | +Inquiry |
Pdgfrb-189M | Recombinant Mouse Pdgfrb Protein, His-tagged | +Inquiry |
PDGFRB-2573H | Recombinant Human PDGFRB Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PDGFRB-1107HCL | Recombinant Human PDGFRB cell lysate | +Inquiry |
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◆ Assay kits | ||
Kit-1618 | PDGFRb Functional Assay Kit | +Inquiry |
Kit-1617 | U2OS PDGFRb Bioassay Kit | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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